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pubmed-article:17946126pubmed:dateCreated2007-10-23lld:pubmed
pubmed-article:17946126pubmed:abstractTextThis paper describes a novel user-guided method for grouping fibers from diffusion tensor MRI tractography into bundles. The method finds fibers, that passing through user-defined ROIs, still fit to the underlying data model given by the diffusion tensor. This is achieved by filtering the data and the ROIs with a kernel derived from a geodesic metric between tensors. A standard approach using binary decisions defining tracts passing through ROIs is critically dependent on ROIs that includes all trace lines of interest. The method described in this paper uses a softer decision mechanism through a kernel which enables grouping of bundles driven less exact, or even single point, ROIs. The method analyzes the responses obtained from the convolution with a kernel function along the fiber with the ROI data. Results in real data shows the feasibility of the approach to fiber bundling.lld:pubmed
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pubmed-article:17946126pubmed:authorpubmed-author:WestinCarl-Fr...lld:pubmed
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pubmed-article:17946126pubmed:authorpubmed-author:San José...lld:pubmed
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pubmed-article:17946126pubmed:dateRevised2010-12-3lld:pubmed
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pubmed-article:17946126pubmed:articleTitleA kernel-based approach for user-guided fiber bundling using diffusion tensor data.lld:pubmed
pubmed-article:17946126pubmed:affiliationLab. of Math. in Imaging, Brigham & Women's Hosp., Boston, MA, USA. rjosest@bwh.harvard.edulld:pubmed
pubmed-article:17946126pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:17946126pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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