| pubmed-article:17923406 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17923406 | lifeskim:mentions | umls-concept:C0014834 | lld:lifeskim |
| pubmed-article:17923406 | lifeskim:mentions | umls-concept:C0007590 | lld:lifeskim |
| pubmed-article:17923406 | lifeskim:mentions | umls-concept:C0243077 | lld:lifeskim |
| pubmed-article:17923406 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
| pubmed-article:17923406 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
| pubmed-article:17923406 | pubmed:issue | 23 | lld:pubmed |
| pubmed-article:17923406 | pubmed:dateCreated | 2007-11-6 | lld:pubmed |
| pubmed-article:17923406 | pubmed:abstractText | A new small molecule inhibitor of bacterial cell division has been discovered using a high-throughput screen in Escherichia coli. Although the lead screening hit (534F6) exhibited modest inhibition of the GTPase activity of FtsZ (20+/-5% at 100microM of compound), a primary target for bacterial cell division inhibitors, several analogs caused potent bacterial growth inhibition with negligible antagonism of FtsZ GTPase activity. A library of analogs has been prepared and several alkyne-tagged photoaffinity probes have been synthesized for use in experiments to elucidate the primary target of this compound. | lld:pubmed |
| pubmed-article:17923406 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17923406 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17923406 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17923406 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17923406 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17923406 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:17923406 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17923406 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17923406 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17923406 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17923406 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17923406 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17923406 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:17923406 | pubmed:issn | 1464-3405 | lld:pubmed |
| pubmed-article:17923406 | pubmed:author | pubmed-author:ShawJared TJT | lld:pubmed |
| pubmed-article:17923406 | pubmed:author | pubmed-author:MukherjeeShub... | lld:pubmed |
| pubmed-article:17923406 | pubmed:author | pubmed-author:UrgaonkarSame... | lld:pubmed |
| pubmed-article:17923406 | pubmed:author | pubmed-author:HebertAlan... | lld:pubmed |
| pubmed-article:17923406 | pubmed:author | pubmed-author:WoodPeter APA | lld:pubmed |
| pubmed-article:17923406 | pubmed:author | pubmed-author:RobinsonCarol... | lld:pubmed |
| pubmed-article:17923406 | pubmed:author | pubmed-author:HoweAndrew... | lld:pubmed |
| pubmed-article:17923406 | pubmed:author | pubmed-author:MazorTaliT | lld:pubmed |
| pubmed-article:17923406 | pubmed:author | pubmed-author:RaychaudhuriD... | lld:pubmed |
| pubmed-article:17923406 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:17923406 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:17923406 | pubmed:volume | 17 | lld:pubmed |
| pubmed-article:17923406 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17923406 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17923406 | pubmed:pagination | 6651-5 | lld:pubmed |
| pubmed-article:17923406 | pubmed:meshHeading | pubmed-meshheading:17923406... | lld:pubmed |
| pubmed-article:17923406 | pubmed:meshHeading | pubmed-meshheading:17923406... | lld:pubmed |
| pubmed-article:17923406 | pubmed:meshHeading | pubmed-meshheading:17923406... | lld:pubmed |
| pubmed-article:17923406 | pubmed:meshHeading | pubmed-meshheading:17923406... | lld:pubmed |
| pubmed-article:17923406 | pubmed:meshHeading | pubmed-meshheading:17923406... | lld:pubmed |
| pubmed-article:17923406 | pubmed:meshHeading | pubmed-meshheading:17923406... | lld:pubmed |
| pubmed-article:17923406 | pubmed:meshHeading | pubmed-meshheading:17923406... | lld:pubmed |
| pubmed-article:17923406 | pubmed:meshHeading | pubmed-meshheading:17923406... | lld:pubmed |
| pubmed-article:17923406 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:17923406 | pubmed:articleTitle | N-Benzyl-3-sulfonamidopyrrolidines as novel inhibitors of cell division in E. coli. | lld:pubmed |
| pubmed-article:17923406 | pubmed:affiliation | Broad Institute of Harvard and MIT, 7 Cambridge Center, Cambridge, MA 02142, USA. | lld:pubmed |
| pubmed-article:17923406 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17923406 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:17923406 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:17923406 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:17923406 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:17923406 | lld:chembl |
| entrez-gene:944786 | entrezgene:pubmed | pubmed-article:17923406 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:17923406 | lld:pubmed |
