Osteoarthritis (OA) affects mainly older people who are more sensitive to adverse effects of classic nonsteroidal anti-inflammatory drugs. Recent publications indicate that topically applied nonsteroidal anti-inflammatory drugs are effective and much safer than their oral analogues.
Department of Pharmacology and Clinical Pharmacology, Ankara University Faculty of Medicine, Sihhiye, 06100 Ankara, Turkey. hergun@medicine.ankara.edu.tr
