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pubmed-article:17920818pubmed:abstractTextBullous pemphigoid (BP) is a subepidermal blistering disease characterized by autoantibodies against the hemidesmosomal proteins, BP180 and BP230. NC16A, a non-collagenous stretch of the BP180 ectodomain is the primary target of pathogenic IgG antibodies. Whereas IgG anti-BP180 autoantibodies play a primary role in the pathogenesis, there is a growing number of data regarding the potential pathogenic roles of IgE class autoantibodies in BP.lld:pubmed
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pubmed-article:17920818pubmed:articleTitleSerum levels of IgE anti-BP180 and anti-BP230 autoantibodies in patients with bullous pemphigoid.lld:pubmed
pubmed-article:17920818pubmed:affiliationDepartment of Dermatology, Graduate School of Medicine, University of Tokyo, Bunkyo, Tokyo, Japan.lld:pubmed
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