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pubmed-article:17918969pubmed:abstractTextWe report the use of desorption electrospray ionization hybrid Fourier transform ion cyclotron resonance mass spectrometry (DESI-FT-ICR-MS) for the analysis of carbohydrates. Spectra of neat carbohydrates are presented along with their mass measurement accuracies and limits of detection. Furthermore, a comparison is made between the analyses of O-linked glycans from mucin by DESI-FT-ICR-MS and matrix-assisted laser desorption/ionization Fourier transform ion cyclotron resonance mass spectrometry. Finally, glycans from mucin are identified by using the high mass measurement accuracy and tandem MS capabilities afforded by the hybrid FT-ICR-MS platform.lld:pubmed
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pubmed-article:17918969pubmed:authorpubmed-author:MuddimanDavid...lld:pubmed
pubmed-article:17918969pubmed:authorpubmed-author:WilliamsTaufi...lld:pubmed
pubmed-article:17918969pubmed:authorpubmed-author:BeremanMichae...lld:pubmed
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pubmed-article:17918969pubmed:year2007lld:pubmed
pubmed-article:17918969pubmed:articleTitleCarbohydrate analysis by desorption electrospray ionization fourier transform ion cyclotron resonance mass spectrometry.lld:pubmed
pubmed-article:17918969pubmed:affiliationW.M Keck FT-ICR Mass Spectrometry Laboratory, Department of Chemistry, North Carolina State University, Raleigh, North Carolina 27695, USA.lld:pubmed
pubmed-article:17918969pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:17918969pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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