pubmed-article:17914459 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:17914459 | lifeskim:mentions | umls-concept:C2717838 | lld:lifeskim |
pubmed-article:17914459 | lifeskim:mentions | umls-concept:C0040649 | lld:lifeskim |
pubmed-article:17914459 | lifeskim:mentions | umls-concept:C1624022 | lld:lifeskim |
pubmed-article:17914459 | lifeskim:mentions | umls-concept:C0851285 | lld:lifeskim |
pubmed-article:17914459 | pubmed:issue | 21 | lld:pubmed |
pubmed-article:17914459 | pubmed:dateCreated | 2007-10-31 | lld:pubmed |
pubmed-article:17914459 | pubmed:abstractText | Transcription by RNA polymerase II is accompanied by dynamic changes in chromatin, including the eviction/deposition of nucleosomes or the covalent modification of histone subunits. This study examined the role of the histone H3/H4 chaperones, Asf1 and HIR, in histone mobility during transcription, with particular focus on the histone exchange pathway, using a dual histone expression system. The results showed that the exchange of H3/H4 normally occurs during transcription by the histone chaperones. Both Asf1 and HIR are important for histone deposition but have a different effect on histone exchange. While Asf1 mediated incorporation of external H3/H4 and renewal of pre-existing histones, HIR opposed it. The balance of two opposing activities might be an important mechanism for determining current chromatin states. | lld:pubmed |
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pubmed-article:17914459 | pubmed:language | eng | lld:pubmed |
pubmed-article:17914459 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:17914459 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:17914459 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:17914459 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:17914459 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:17914459 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:17914459 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:17914459 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:17914459 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:17914459 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:17914459 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:17914459 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:17914459 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:17914459 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:17914459 | pubmed:month | Oct | lld:pubmed |
pubmed-article:17914459 | pubmed:issn | 1460-2075 | lld:pubmed |
pubmed-article:17914459 | pubmed:author | pubmed-author:HanJeung-Whan... | lld:pubmed |
pubmed-article:17914459 | pubmed:author | pubmed-author:ChoEun-JungEJ | lld:pubmed |
pubmed-article:17914459 | pubmed:author | pubmed-author:KimHye-JinHJ | lld:pubmed |
pubmed-article:17914459 | pubmed:author | pubmed-author:YounHong-DukH... | lld:pubmed |
pubmed-article:17914459 | pubmed:author | pubmed-author:SeolJa-HwanJH | lld:pubmed |
pubmed-article:17914459 | pubmed:issnType | Electronic | lld:pubmed |
pubmed-article:17914459 | pubmed:day | 31 | lld:pubmed |
pubmed-article:17914459 | pubmed:volume | 26 | lld:pubmed |
pubmed-article:17914459 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:17914459 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:17914459 | pubmed:pagination | 4467-74 | lld:pubmed |
pubmed-article:17914459 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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pubmed-article:17914459 | pubmed:year | 2007 | lld:pubmed |
pubmed-article:17914459 | pubmed:articleTitle | Histone chaperones regulate histone exchange during transcription. | lld:pubmed |
pubmed-article:17914459 | pubmed:affiliation | College of Pharmacy, Sungkyunkwan University, Suwon, Gyeonggi-do, Republic of Korea. | lld:pubmed |
pubmed-article:17914459 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:17914459 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |