| pubmed-article:17886473 | pubmed:abstractText | The degeneration of mesocorticolimbic dopaminergic system is assumed to disturbed motivated behavior, intellectual impairment and depression in Parkinson's disease (PD), and there is growing interest in its role in impaired emotional and social behaviors. Patients with PD demonstrated the impairment of social cognition by the test of facial expression recognition and the Iowa gambling task (IGT). However, the result of facial expressions cognition in patients with juvenile parkinsonism (JP) is not significantly different from normal controls. In the IGT, the JP group learned better performance than the PD group. The relatively spared social cognition in JP as compared with PD could be attributed that dopaminergic depletion being more severe in the nigrostriatal system than in the mesocorticolimbic system. | lld:pubmed |
