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pubmed-article:1788536pubmed:abstractTextOccupational exposure to cyclohexanone was studied for 59 workers through the analysis of environmental air, alveolar air, and urinary cyclohexanol. Environmental cyclohexanone exposure was measured by personal sampling with a carbon-felt passive dosimeter. Cyclohexanone in alveolar air and cyclohexanol in urine were determined with gas chromatography with a flame ionization detector. The end-of-shift urinary cyclohexanol levels correlated well with the time-weighted average environmental cyclohexanone values (r = 0.66). Urinary cyclohexanol corrected for creatinine correlated best with cyclohexanone in air (r = 0.77); when corrected for specific gravity, it gave a similar correlation coefficient (r = 0.73). When the time-weighted average of the exposure was 25 ppm, the corresponding calculated concentration for urinary cyclohexanol was 54.5 mg/1, 23.3 mg/g of creatinine, or 43.5 mg/l at a specific gravity of 1.018. The relationship between cyclohexanone exposure and its concentration in exhaled breath was found to be poorer than that for cyclohexanone exposure and the urinary metabolite (r = 0.51).lld:pubmed
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pubmed-article:1788536pubmed:authorpubmed-author:TanK TKTlld:pubmed
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pubmed-article:1788536pubmed:articleTitleMonitoring of exposure to cyclohexanone through the analysis of breath and urine.lld:pubmed
pubmed-article:1788536pubmed:affiliationDepartment of Community Occupational and Family Medicine, National University of Singapore.lld:pubmed
pubmed-article:1788536pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:1788536pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed