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pubmed-article:17877726rdf:typepubmed:Citationlld:pubmed
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pubmed-article:17877726pubmed:issue3lld:pubmed
pubmed-article:17877726pubmed:dateCreated2008-2-6lld:pubmed
pubmed-article:17877726pubmed:abstractTextPatients with HIV infection are frequently infected with hepatitis viruses, which are presently the major cause of mortality in HIV-infected patients after the widespread use of highly active antiretrovirus therapy. We previously reported that approximately 20% of HIV-positive Japanese patients were also infected with hepatitis C virus (HCV). Hepatitis B virus (HBV) infection may also be an impediment to a good course of treatment for HIV-infected patients, because of recurrent liver injuries and a common effectiveness of some anti-HIV drugs on HBV replication. However, the status of co-infection with HIV and HBV in Japan is unclear. We conducted a nationwide survey to determine the prevalence of HIV-HBV co-infection by distributing a questionnaire to the hospitals belonging to the HIV/AIDS Network of Japan. Among the 5998patients reported to be HIV positive, 377 (6.4%) were positive for the hepatitis B surface antigen. Homosexual men accounted for two-thirds (70.8%) of the HIV-HBV co-infected patients, distinct from HIV-HCV co-infection in Japan in which most of the HIV-HCV co-infected patients were recipients of blood products. One-third of HIV-HBV co-infected patients had elevated serum alanine aminotransferase levels at least once during the 1-year observation period. In conclusion, some HIV-infected Japanese patients also have HBV infection and liver disease. A detailed analysis of the progression and activity of liver disease in co-infected patients is needed.lld:pubmed
pubmed-article:17877726pubmed:languageenglld:pubmed
pubmed-article:17877726pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
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pubmed-article:17877726pubmed:issn1386-6346lld:pubmed
pubmed-article:17877726pubmed:authorpubmed-author:KatoMichioMlld:pubmed
pubmed-article:17877726pubmed:authorpubmed-author:KikuchiYoshim...lld:pubmed
pubmed-article:17877726pubmed:authorpubmed-author:KoikeKazuhiko...lld:pubmed
pubmed-article:17877726pubmed:authorpubmed-author:TakamatsuJunk...lld:pubmed
pubmed-article:17877726pubmed:authorpubmed-author:TsutsumiTakey...lld:pubmed
pubmed-article:17877726pubmed:authorpubmed-author:FujieHajimeHlld:pubmed
pubmed-article:17877726pubmed:authorpubmed-author:ShintaniYoshi...lld:pubmed
pubmed-article:17877726pubmed:authorpubmed-author:KyojiMoriyaMlld:pubmed
pubmed-article:17877726pubmed:authorpubmed-author:YotsuyanagiHi...lld:pubmed
pubmed-article:17877726pubmed:authorpubmed-author:MiyoshiHideyu...lld:pubmed
pubmed-article:17877726pubmed:issnTypePrintlld:pubmed
pubmed-article:17877726pubmed:volume38lld:pubmed
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pubmed-article:17877726pubmed:authorsCompleteYlld:pubmed
pubmed-article:17877726pubmed:pagination310-4lld:pubmed
pubmed-article:17877726pubmed:year2008lld:pubmed
pubmed-article:17877726pubmed:articleTitlePrevalence of hepatitis B virus infection in Japanese patients with HIV.lld:pubmed
pubmed-article:17877726pubmed:affiliationDepartment of Internal Medicine, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.lld:pubmed
pubmed-article:17877726pubmed:publicationTypeJournal Articlelld:pubmed
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