| pubmed-article:17870543 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17870543 | lifeskim:mentions | umls-concept:C0279516 | lld:lifeskim |
| pubmed-article:17870543 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
| pubmed-article:17870543 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:17870543 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:17870543 | lifeskim:mentions | umls-concept:C0392747 | lld:lifeskim |
| pubmed-article:17870543 | lifeskim:mentions | umls-concept:C1554963 | lld:lifeskim |
| pubmed-article:17870543 | lifeskim:mentions | umls-concept:C1259969 | lld:lifeskim |
| pubmed-article:17870543 | lifeskim:mentions | umls-concept:C0243072 | lld:lifeskim |
| pubmed-article:17870543 | pubmed:issue | 24 | lld:pubmed |
| pubmed-article:17870543 | pubmed:dateCreated | 2007-10-22 | lld:pubmed |
| pubmed-article:17870543 | pubmed:abstractText | Continuing from our ongoing effort in modifying aminoglycoside antibiotics with the goal of counteracting drug resistant bacteria, we have further derivatized pyranmycin, a neomycin class aminoglycoside antibiotic, with modifications at O-6 and N-1 positions. The revealed SAR results demonstrated that the antibacterial activity of pyranmycin can be modulated by different acylic substituents at O-6. Among these results, the 6-O-aminoethyl derivative, JT050, showed effective activity against resistant strain Escherichia coli (pTZ19U-3) and E. coli (pSF815), which provides insight into further structural modifications. | lld:pubmed |
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| pubmed-article:17870543 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:17870543 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17870543 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17870543 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17870543 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17870543 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:17870543 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17870543 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17870543 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17870543 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17870543 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17870543 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17870543 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17870543 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:17870543 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17870543 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:17870543 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17870543 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17870543 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17870543 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:17870543 | pubmed:issn | 1464-3391 | lld:pubmed |
| pubmed-article:17870543 | pubmed:author | pubmed-author:LoyMM | lld:pubmed |
| pubmed-article:17870543 | pubmed:author | pubmed-author:ChangCheng-We... | lld:pubmed |
| pubmed-article:17870543 | pubmed:author | pubmed-author:ChenHsiao-Nun... | lld:pubmed |
| pubmed-article:17870543 | pubmed:author | pubmed-author:ChiangFang-IF... | lld:pubmed |
| pubmed-article:17870543 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:17870543 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:17870543 | pubmed:volume | 15 | lld:pubmed |
| pubmed-article:17870543 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17870543 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17870543 | pubmed:pagination | 7711-9 | lld:pubmed |
| pubmed-article:17870543 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:17870543 | pubmed:meshHeading | pubmed-meshheading:17870543... | lld:pubmed |
| pubmed-article:17870543 | pubmed:meshHeading | pubmed-meshheading:17870543... | lld:pubmed |
| pubmed-article:17870543 | pubmed:meshHeading | pubmed-meshheading:17870543... | lld:pubmed |
| pubmed-article:17870543 | pubmed:meshHeading | pubmed-meshheading:17870543... | lld:pubmed |
| pubmed-article:17870543 | pubmed:meshHeading | pubmed-meshheading:17870543... | lld:pubmed |
| pubmed-article:17870543 | pubmed:meshHeading | pubmed-meshheading:17870543... | lld:pubmed |
| pubmed-article:17870543 | pubmed:meshHeading | pubmed-meshheading:17870543... | lld:pubmed |
| pubmed-article:17870543 | pubmed:meshHeading | pubmed-meshheading:17870543... | lld:pubmed |
| pubmed-article:17870543 | pubmed:meshHeading | pubmed-meshheading:17870543... | lld:pubmed |
| pubmed-article:17870543 | pubmed:meshHeading | pubmed-meshheading:17870543... | lld:pubmed |
| pubmed-article:17870543 | pubmed:meshHeading | pubmed-meshheading:17870543... | lld:pubmed |
| pubmed-article:17870543 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:17870543 | pubmed:articleTitle | Synthesis and antibacterial activity of pyranmycin derivatives with N-1 and O-6 modifications. | lld:pubmed |
| pubmed-article:17870543 | pubmed:affiliation | Department of Chemistry and Biochemistry, Utah State University, 0300 Old Main Hill, Logan, UT 84322-0300, USA. | lld:pubmed |
| pubmed-article:17870543 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17870543 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:17870543 | lld:chembl |
