| pubmed-article:1782417 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1782417 | lifeskim:mentions | umls-concept:C0999699 | lld:lifeskim |
| pubmed-article:1782417 | lifeskim:mentions | umls-concept:C0036226 | lld:lifeskim |
| pubmed-article:1782417 | lifeskim:mentions | umls-concept:C0225828 | lld:lifeskim |
| pubmed-article:1782417 | lifeskim:mentions | umls-concept:C0025270 | lld:lifeskim |
| pubmed-article:1782417 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:1782417 | lifeskim:mentions | umls-concept:C0596235 | lld:lifeskim |
| pubmed-article:1782417 | lifeskim:mentions | umls-concept:C0205171 | lld:lifeskim |
| pubmed-article:1782417 | lifeskim:mentions | umls-concept:C1140999 | lld:lifeskim |
| pubmed-article:1782417 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:1782417 | pubmed:dateCreated | 1992-3-13 | lld:pubmed |
| pubmed-article:1782417 | pubmed:abstractText | We investigated the effect of 2-methyl-1,4-naphtoquinone (Menadione) on sarcoplasmic reticulum (SR) Ca2+ content and electrically stimulated contractions (ESCs) of single isolated myocytes of guinea-pig ventricular myocardium. The contractures initiated by means of microinjections of caffeine into the close vicinity of the cell were used as an indirect index of the SR Ca2+ content. Superfusion of the cells for 45 min with Menadione resulted in gradual disappearance of contractile responses to caffeine, prolongation of time to peak amplitude of ESCs by 48 +/- 15% and complete inhibition of postrest and postextrasystolic potentiation. These results are consistent with those of Floreani and Carpenedo (7) who found that Menadione strongly inhibits the SR Ca2+ ATPase. Despite depletion of the SR Ca2+ the amplitude of ESCs did not change which suggests that contractions were initiated in the cells treated with Menadione by Ca2+ derived from the sources other than the SR. | lld:pubmed |
| pubmed-article:1782417 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1782417 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1782417 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1782417 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1782417 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1782417 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1782417 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:1782417 | pubmed:issn | 0867-5910 | lld:pubmed |
| pubmed-article:1782417 | pubmed:author | pubmed-author:LewartowskiBB | lld:pubmed |
| pubmed-article:1782417 | pubmed:author | pubmed-author:ZdanowskiKK | lld:pubmed |
| pubmed-article:1782417 | pubmed:author | pubmed-author:WolskaB MBM | lld:pubmed |
| pubmed-article:1782417 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1782417 | pubmed:volume | 42 | lld:pubmed |
| pubmed-article:1782417 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1782417 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1782417 | pubmed:pagination | 221-34 | lld:pubmed |
| pubmed-article:1782417 | pubmed:dateRevised | 2003-11-14 | lld:pubmed |
| pubmed-article:1782417 | pubmed:meshHeading | pubmed-meshheading:1782417-... | lld:pubmed |
| pubmed-article:1782417 | pubmed:meshHeading | pubmed-meshheading:1782417-... | lld:pubmed |
| pubmed-article:1782417 | pubmed:meshHeading | pubmed-meshheading:1782417-... | lld:pubmed |
| pubmed-article:1782417 | pubmed:meshHeading | pubmed-meshheading:1782417-... | lld:pubmed |
| pubmed-article:1782417 | pubmed:meshHeading | pubmed-meshheading:1782417-... | lld:pubmed |
| pubmed-article:1782417 | pubmed:meshHeading | pubmed-meshheading:1782417-... | lld:pubmed |
| pubmed-article:1782417 | pubmed:meshHeading | pubmed-meshheading:1782417-... | lld:pubmed |
| pubmed-article:1782417 | pubmed:meshHeading | pubmed-meshheading:1782417-... | lld:pubmed |
| pubmed-article:1782417 | pubmed:meshHeading | pubmed-meshheading:1782417-... | lld:pubmed |
| pubmed-article:1782417 | pubmed:meshHeading | pubmed-meshheading:1782417-... | lld:pubmed |
| pubmed-article:1782417 | pubmed:meshHeading | pubmed-meshheading:1782417-... | lld:pubmed |
| pubmed-article:1782417 | pubmed:year | 1991 | lld:pubmed |
| pubmed-article:1782417 | pubmed:articleTitle | The effect of menadione on sarcoplasmic reticulum Ca2+ and contractions of single guinea-pig cardiomyocytes. | lld:pubmed |
| pubmed-article:1782417 | pubmed:affiliation | Department of Clinical Physiology, Medical Center of Postgraduate Education, Warsaw, Poland. | lld:pubmed |
| pubmed-article:1782417 | pubmed:publicationType | Journal Article | lld:pubmed |
