pubmed-article:1773863 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:1773863 | lifeskim:mentions | umls-concept:C0999405 | lld:lifeskim |
pubmed-article:1773863 | lifeskim:mentions | umls-concept:C1000793 | lld:lifeskim |
pubmed-article:1773863 | lifeskim:mentions | umls-concept:C0021755 | lld:lifeskim |
pubmed-article:1773863 | lifeskim:mentions | umls-concept:C0033268 | lld:lifeskim |
pubmed-article:1773863 | pubmed:issue | 4 | lld:pubmed |
pubmed-article:1773863 | pubmed:dateCreated | 1992-3-4 | lld:pubmed |
pubmed-article:1773863 | pubmed:abstractText | A homologous thymocyte costimulatory assay using thymocytes from a South American opossum (Monodelphis domestica) detected and measured interleukin-1 (IL-1). Opossum IL-1 was obtained from lipopolysaccharide-stimulated macrophage and skin cultures and its molecular weight was determined to be 15,000 to 17,000. Opossum IL-1 did not stimulate proliferation of murine thymocytes; conversely, neither human nor murine IL-1 stimulated opossum thymocytes. Anti-human IL-1 antibodies were also not reactive with opossum IL-1. These observations indicate that there is no serological and functional crossreactivity between the opossum (marsupial mammals) and human and mouse (eutherian mammals) in an IL-1/thymocyte system. This is unusual because such crossreactivity occurs between rodents and distant, nonmammalian species. M. domestica has been used in our laboratory as a model for photobiological research; studies on IL-1 may provide insight into the relationship of immunosuppression and tumorigenesis induced by ultraviolet radiation. | lld:pubmed |
pubmed-article:1773863 | pubmed:language | eng | lld:pubmed |
pubmed-article:1773863 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1773863 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:1773863 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1773863 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1773863 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1773863 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:1773863 | pubmed:issn | 0145-305X | lld:pubmed |
pubmed-article:1773863 | pubmed:author | pubmed-author:NEWP FPF | lld:pubmed |
pubmed-article:1773863 | pubmed:author | pubmed-author:BrozekC MCM | lld:pubmed |
pubmed-article:1773863 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:1773863 | pubmed:volume | 15 | lld:pubmed |
pubmed-article:1773863 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:1773863 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:1773863 | pubmed:pagination | 401-12 | lld:pubmed |
pubmed-article:1773863 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:1773863 | pubmed:year | 1991 | lld:pubmed |
pubmed-article:1773863 | pubmed:articleTitle | Production of interleukin-1 in a South American opossum (Monodelphis domestica). | lld:pubmed |
pubmed-article:1773863 | pubmed:affiliation | Photomedicine Program, Lovelace Medical Foundation, Albuquerque, NM. | lld:pubmed |
pubmed-article:1773863 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:1773863 | pubmed:publicationType | Comparative Study | lld:pubmed |