We examined the role of transforming growth factor-beta in urothelial and bladder development. Transforming growth factor-beta signaling was attenuated in the urothelial compartment and the subsequent effects were examined in a tissue recombination model.
Division of Pediatric Urology, Department of Urologic Surgery, Vanderbilt Children's Hospital, Nashville, Tennessee 37232-2765, USA. siam.oottamasathien@vanderbilt.edu