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pubmed-article:17700153pubmed:abstractTextThe success of pancreatic islet transplantation is limited because of immune rejection of allogeneic transplanted tissue and potential adverse side effects of nonspecific immunosuppression. Local expression of an immunosuppressive agent at the site of islet transplant could promote long-term engraftment without associated systemic side effects.lld:pubmed
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pubmed-article:17700153pubmed:articleTitleImmunomodulation by adenoviral-mediated SCD40-Ig gene therapy for mouse allogeneic islet transplantation.lld:pubmed
pubmed-article:17700153pubmed:affiliationDepartment of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine Pittsburgh, PA 15261, USA.lld:pubmed
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