Plasma levels of N-terminal pro-brain natriuretic peptide (NT-pro BNP) are increased in patients with chronic heart failure (CHF). Beta-blockers (BB) may influence these levels but it is unclear whether changes in NT-pro BNP reflect concomitant changes in prognosis.
Prognostic importance of plasma NT-pro BNP in chronic heart failure in patients treated with a beta-blocker: results from the Carvedilol Or Metoprolol European Trial (COMET) trial.
Department of Emergency and Cardiovascular Medicine Sahlgrenska Academy, Göteborg University, Göteborg, Sweden, and Department of Cardiology, La Pitié-Salpétrière Hospital, Paris, France.
