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pubmed-article:17685743pubmed:abstractTextVery few studies have investigated clinical features associated with treatment-resistant depression (TRD) defined as failure of at least 2 consecutive antidepressant trials. The primary objective of this multicenter study was to identify specific clinical and demographic factors associated with TRD in a large sample of patients with major depressive episodes that failed to reach response or remission after at least 2 consecutive adequate antidepressant treatments.lld:pubmed
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pubmed-article:17685743pubmed:articleTitleClinical factors associated with treatment resistance in major depressive disorder: results from a European multicenter study.lld:pubmed
pubmed-article:17685743pubmed:affiliationDepartment of Psychiatry, Erasme Hospital, Université Libre de Bruxelles, Brussels, Belgium. dsouery@ulb.ac.belld:pubmed
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