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pubmed-article:17663690pubmed:abstractTextHBL and HCC are the most common hepatic malignancies in children. The role of OLT in children with HCC is still a matter of debate. The aim of this study was to review our experience of OLT for HCC. Medical records of patients (<18 yr) who underwent OLT for HCC were reviewed and compared to children who underwent OLT for HBL and for indications other than malignancy. There were 25 patients: HCC (10 cases) and HBL (15 cases). The actuarial patient survival for HCC at one and five yr was 100% and 83.3%, for the HBL group the survival was 86.7% at both one and five yr, and for indications (n=377) other than malignancy the patient survival for pediatric OLT at our center was 87.7% and 84.7% at one and five yr, respectively. The actuarial recurrence free survival at five yr was 83.3% for HCC and 66.8% for HBL. In conclusion, OLT is a good therapeutic modality for children with HCC and HBL.lld:pubmed
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pubmed-article:17663690pubmed:dateRevised2008-5-15lld:pubmed
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pubmed-article:17663690pubmed:articleTitleOutcomes of transplantation in children with primary hepatic malignancy.lld:pubmed
pubmed-article:17663690pubmed:affiliationDivisions of Transplantation, Lucile Salter Packard Children's Hospital and Stanford University School of Medicine, Stanford, CA 94304, USA.lld:pubmed
pubmed-article:17663690pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:17663690pubmed:publicationTypeComparative Studylld:pubmed
pubmed-article:17663690pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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