pubmed-article:17659871 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:17659871 | lifeskim:mentions | umls-concept:C0007634 | lld:lifeskim |
pubmed-article:17659871 | lifeskim:mentions | umls-concept:C0043119 | lld:lifeskim |
pubmed-article:17659871 | lifeskim:mentions | umls-concept:C1120843 | lld:lifeskim |
pubmed-article:17659871 | lifeskim:mentions | umls-concept:C0021467 | lld:lifeskim |
pubmed-article:17659871 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
pubmed-article:17659871 | lifeskim:mentions | umls-concept:C1366876 | lld:lifeskim |
pubmed-article:17659871 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
pubmed-article:17659871 | lifeskim:mentions | umls-concept:C0021469 | lld:lifeskim |
pubmed-article:17659871 | lifeskim:mentions | umls-concept:C0439831 | lld:lifeskim |
pubmed-article:17659871 | lifeskim:mentions | umls-concept:C1143207 | lld:lifeskim |
pubmed-article:17659871 | pubmed:issue | 18 | lld:pubmed |
pubmed-article:17659871 | pubmed:dateCreated | 2007-8-22 | lld:pubmed |
pubmed-article:17659871 | pubmed:abstractText | The p38 mitogen-activated protein kinase inhibitor VX-745 is prepared rapidly and efficiently in a four-step sequence using a combination of conductive heating and microwave-mediated steps. Its inhibitory activity was confirmed in hTERT immortalized HCA2 and WS dermal fibroblasts at 0.5-1.0 microM concentration by ELISA and immunoblot assay, and displays excellent kinase selectivity over the related stress-activated kinase JNK. | lld:pubmed |
pubmed-article:17659871 | pubmed:language | eng | lld:pubmed |
pubmed-article:17659871 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:17659871 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:17659871 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:17659871 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:17659871 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:17659871 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:17659871 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:17659871 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:17659871 | pubmed:month | Sep | lld:pubmed |
pubmed-article:17659871 | pubmed:issn | 0960-894X | lld:pubmed |
pubmed-article:17659871 | pubmed:author | pubmed-author:KiplingDavidD | lld:pubmed |
pubmed-article:17659871 | pubmed:author | pubmed-author:BagleyMark... | lld:pubmed |
pubmed-article:17659871 | pubmed:author | pubmed-author:DavisTerenceT | lld:pubmed |
pubmed-article:17659871 | pubmed:author | pubmed-author:DixMatthew... | lld:pubmed |
pubmed-article:17659871 | pubmed:author | pubmed-author:RokickiMichal... | lld:pubmed |
pubmed-article:17659871 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:17659871 | pubmed:day | 15 | lld:pubmed |
pubmed-article:17659871 | pubmed:volume | 17 | lld:pubmed |
pubmed-article:17659871 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:17659871 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:17659871 | pubmed:pagination | 5107-10 | lld:pubmed |
pubmed-article:17659871 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
pubmed-article:17659871 | pubmed:meshHeading | pubmed-meshheading:17659871... | lld:pubmed |
pubmed-article:17659871 | pubmed:meshHeading | pubmed-meshheading:17659871... | lld:pubmed |
pubmed-article:17659871 | pubmed:meshHeading | pubmed-meshheading:17659871... | lld:pubmed |
pubmed-article:17659871 | pubmed:meshHeading | pubmed-meshheading:17659871... | lld:pubmed |
pubmed-article:17659871 | pubmed:meshHeading | pubmed-meshheading:17659871... | lld:pubmed |
pubmed-article:17659871 | pubmed:meshHeading | pubmed-meshheading:17659871... | lld:pubmed |
pubmed-article:17659871 | pubmed:meshHeading | pubmed-meshheading:17659871... | lld:pubmed |
pubmed-article:17659871 | pubmed:year | 2007 | lld:pubmed |
pubmed-article:17659871 | pubmed:articleTitle | Rapid synthesis of VX-745: p38 MAP kinase inhibition in Werner syndrome cells. | lld:pubmed |
pubmed-article:17659871 | pubmed:affiliation | School of Chemistry, Main Building, Cardiff University, Park Place, Cardiff CF10 3AT, UK. Bagleymc@cardiff.ac.uk | lld:pubmed |
pubmed-article:17659871 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:17659871 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:17659871 | lld:chembl |