| pubmed-article:17658779 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17658779 | lifeskim:mentions | umls-concept:C0013227 | lld:lifeskim |
| pubmed-article:17658779 | lifeskim:mentions | umls-concept:C0012408 | lld:lifeskim |
| pubmed-article:17658779 | lifeskim:mentions | umls-concept:C0181586 | lld:lifeskim |
| pubmed-article:17658779 | lifeskim:mentions | umls-concept:C0243077 | lld:lifeskim |
| pubmed-article:17658779 | lifeskim:mentions | umls-concept:C1880355 | lld:lifeskim |
| pubmed-article:17658779 | lifeskim:mentions | umls-concept:C0450254 | lld:lifeskim |
| pubmed-article:17658779 | lifeskim:mentions | umls-concept:C0205202 | lld:lifeskim |
| pubmed-article:17658779 | lifeskim:mentions | umls-concept:C0088415 | lld:lifeskim |
| pubmed-article:17658779 | pubmed:issue | 17 | lld:pubmed |
| pubmed-article:17658779 | pubmed:dateCreated | 2007-8-16 | lld:pubmed |
| pubmed-article:17658779 | pubmed:abstractText | Since utilization of menaquinone in the electron transport system is a characteristic of Gram-positive organisms, the 1,4-dihydroxy-2-naphthoate prenyltransferase (MenA) inhibitors 1a and 2a act as selective antibacterial agents against organisms such as methicillin-resistant Stapylococcus aureus (MRSA), Staphylococcus epidermidis (MRSE), and Mycobacterium spp. Growth of drug-resistant Gram-positive organisms was sensitive to the MenA inhibitors, indicating that menaquinone synthesis is a valid new drug target in Gram-positive organisms. | lld:pubmed |
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| pubmed-article:17658779 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17658779 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17658779 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:17658779 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17658779 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:17658779 | pubmed:issn | 0022-2623 | lld:pubmed |
| pubmed-article:17658779 | pubmed:author | pubmed-author:CrickDean CDC | lld:pubmed |
| pubmed-article:17658779 | pubmed:author | pubmed-author:PrabagaranNar... | lld:pubmed |
| pubmed-article:17658779 | pubmed:author | pubmed-author:KurosuMichioM | lld:pubmed |
| pubmed-article:17658779 | pubmed:author | pubmed-author:BiswasKallolm... | lld:pubmed |
| pubmed-article:17658779 | pubmed:author | pubmed-author:DhimanRakeshR | lld:pubmed |
| pubmed-article:17658779 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17658779 | pubmed:day | 23 | lld:pubmed |
| pubmed-article:17658779 | pubmed:volume | 50 | lld:pubmed |
| pubmed-article:17658779 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17658779 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17658779 | pubmed:pagination | 3973-5 | lld:pubmed |
| pubmed-article:17658779 | pubmed:dateRevised | 2011-1-10 | lld:pubmed |
| pubmed-article:17658779 | pubmed:meshHeading | pubmed-meshheading:17658779... | lld:pubmed |
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| pubmed-article:17658779 | pubmed:meshHeading | pubmed-meshheading:17658779... | lld:pubmed |
| pubmed-article:17658779 | pubmed:meshHeading | pubmed-meshheading:17658779... | lld:pubmed |
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| pubmed-article:17658779 | pubmed:meshHeading | pubmed-meshheading:17658779... | lld:pubmed |
| pubmed-article:17658779 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:17658779 | pubmed:articleTitle | Discovery of 1,4-dihydroxy-2-naphthoate [corrected] prenyltransferase inhibitors: new drug leads for multidrug-resistant gram-positive pathogens. | lld:pubmed |
| pubmed-article:17658779 | pubmed:affiliation | Department of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, 1682 Campus Delivery, Fort Collins, Colorado 80523-1682, USA. michio.kurosu@colostate.edu | lld:pubmed |
| pubmed-article:17658779 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17658779 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:17658779 | lld:chembl |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:17658779 | lld:pubmed |
