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pubmed-article:17621650pubmed:abstractTextMethylenetetrahydrofolate reductase (MTHFR) of the folate metabolism pathway is a candidate gene for neural tube defects (NTDs). Frequency of the second common polymorphism, A1298C, in the MTHFR gene is not well known in Mexico. Conflicting results exist regarding the association of A1298C-MTHFR with NTDs. One explanation for this controversy might be that alleles are differently distributed among various populations. The aim of the study was to determine the frequency of the A1298C-MTHFR polymorphism and its association with NTDs in a population of Yucatan, Mexico.lld:pubmed
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pubmed-article:17621650pubmed:copyrightInfo2007 Wiley-Liss, Inc.lld:pubmed
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pubmed-article:17621650pubmed:articleTitleA1298C polymorphism of the MTHFR gene and neural tube defects in the state of Yucatan, Mexico.lld:pubmed
pubmed-article:17621650pubmed:affiliationLaboratorio de Genética, Centro de Investigaciones Regionales, Universidad Autónoma de Yucatán, Yucatán, México. lizbeth@uady.mxlld:pubmed
pubmed-article:17621650pubmed:publicationTypeJournal Articlelld:pubmed
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