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pubmed-article:1761417pubmed:abstractTextComplete 1H and 13C NMR assignments are presented for eremomycin (1) and some of its desglycosylated derivatives 2, 3 and compared to the structurally closely related glycopeptide vancomycin. Primary structure and stereochemistry of eremomycin is corroborated by the present high field total correlation spectroscopy, NOESY and heteronuclear multiple-bond correlation NMR methods. A rough motional characterization of the title compound is attempted by 13C-T1 and 13C-[1H] NOE measurements. Dimerization of eremomycin is observed both in DMSO-d6-CCl4 and D2O solutions. Complexation with cell wall analogue dipeptide Ac-D-Ala-D-Ala is also demonstrated.lld:pubmed
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pubmed-article:1761417pubmed:pagination1208-21lld:pubmed
pubmed-article:1761417pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:1761417pubmed:articleTitleAn NMR study of eremomycin and its derivatives. Full 1H and 13C assignment, motional behavior, dimerization and complexation with Ac-D-Ala-D-Ala.lld:pubmed
pubmed-article:1761417pubmed:affiliationResearch Group for Antibiotics, Hungarian Academy of Sciences, Debrecen.lld:pubmed
pubmed-article:1761417pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:1761417pubmed:publicationTypeComparative Studylld:pubmed
pubmed-article:1761417pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed