| pubmed-article:17599432 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17599432 | lifeskim:mentions | umls-concept:C1522564 | lld:lifeskim |
| pubmed-article:17599432 | lifeskim:mentions | umls-concept:C0232804 | lld:lifeskim |
| pubmed-article:17599432 | lifeskim:mentions | umls-concept:C0441471 | lld:lifeskim |
| pubmed-article:17599432 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:17599432 | lifeskim:mentions | umls-concept:C0475224 | lld:lifeskim |
| pubmed-article:17599432 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:17599432 | pubmed:dateCreated | 2007-6-29 | lld:pubmed |
| pubmed-article:17599432 | pubmed:abstractText | Effects of cardiovascular dysfunction on renal function have been poorly characterized. Therefore, we investigated the relation between a first ischemic cardiac event and long-term renal function changes in the general population from the PREVEND study. We studied 6,360 subjects with a total follow-up duration of 27.017 subject-years. The estimated mean proportional increase in serum creatinine after a first ischemic cardiac event was 3.1% compared with 0.4% per year of follow-up in subjects without such an event (p = 0.005). This represented a significantly larger decrease in estimated glomerular filtration rate after the event in subjects with an event versus the decrease in subjects without a first ischemic cardiac event (2.2 vs 0.5 ml/min/1.73 m(2)/year of follow-up, p = 0.006). In multivariate analysis with adjustment for renal risk factors, this event showed an independent association with serum creatinine change. In conclusion, a first ischemic cardiac event appears to enhance the natural decrease in renal function. Because even mild renal dysfunction should be considered a major cardiovascular risk factor after myocardial infarction, increased renal function loss after an ischemic cardiac event could add to the risk for subsequent cardiovascular morbidity, thus closing a vicious circle. | lld:pubmed |
| pubmed-article:17599432 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17599432 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17599432 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:17599432 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17599432 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17599432 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:17599432 | pubmed:issn | 0002-9149 | lld:pubmed |
| pubmed-article:17599432 | pubmed:author | pubmed-author:van... | lld:pubmed |
| pubmed-article:17599432 | pubmed:author | pubmed-author:de JongPaul... | lld:pubmed |
| pubmed-article:17599432 | pubmed:author | pubmed-author:de ZeeuwDickD | lld:pubmed |
| pubmed-article:17599432 | pubmed:author | pubmed-author:van... | lld:pubmed |
| pubmed-article:17599432 | pubmed:author | pubmed-author:HillegeHans... | lld:pubmed |
| pubmed-article:17599432 | pubmed:author | pubmed-author:de... | lld:pubmed |
| pubmed-article:17599432 | pubmed:author | pubmed-author:EijkelkampWou... | lld:pubmed |
| pubmed-article:17599432 | pubmed:author | pubmed-author:GansevoortRon... | lld:pubmed |
| pubmed-article:17599432 | pubmed:author | pubmed-author:Prevention... | lld:pubmed |
| pubmed-article:17599432 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17599432 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:17599432 | pubmed:volume | 100 | lld:pubmed |
| pubmed-article:17599432 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17599432 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17599432 | pubmed:pagination | 7-12 | lld:pubmed |
| pubmed-article:17599432 | pubmed:meshHeading | pubmed-meshheading:17599432... | lld:pubmed |
| pubmed-article:17599432 | pubmed:meshHeading | pubmed-meshheading:17599432... | lld:pubmed |
| pubmed-article:17599432 | pubmed:meshHeading | pubmed-meshheading:17599432... | lld:pubmed |
| pubmed-article:17599432 | pubmed:meshHeading | pubmed-meshheading:17599432... | lld:pubmed |
| pubmed-article:17599432 | pubmed:meshHeading | pubmed-meshheading:17599432... | lld:pubmed |
| pubmed-article:17599432 | pubmed:meshHeading | pubmed-meshheading:17599432... | lld:pubmed |
| pubmed-article:17599432 | pubmed:meshHeading | pubmed-meshheading:17599432... | lld:pubmed |
| pubmed-article:17599432 | pubmed:meshHeading | pubmed-meshheading:17599432... | lld:pubmed |
| pubmed-article:17599432 | pubmed:meshHeading | pubmed-meshheading:17599432... | lld:pubmed |
| pubmed-article:17599432 | pubmed:meshHeading | pubmed-meshheading:17599432... | lld:pubmed |
| pubmed-article:17599432 | pubmed:meshHeading | pubmed-meshheading:17599432... | lld:pubmed |
| pubmed-article:17599432 | pubmed:meshHeading | pubmed-meshheading:17599432... | lld:pubmed |
| pubmed-article:17599432 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:17599432 | pubmed:articleTitle | Effect of first myocardial ischemic event on renal function. | lld:pubmed |
| pubmed-article:17599432 | pubmed:affiliation | Department of Clinical Pharmacology, Division of Nephrology, University Medical Center Groningen, Groningen, The Netherlands. eijkelkamp@cs.com | lld:pubmed |
| pubmed-article:17599432 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17599432 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:17599432 | lld:pubmed |
