pubmed-article:17559649 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:17559649 | lifeskim:mentions | umls-concept:C0205245 | lld:lifeskim |
pubmed-article:17559649 | lifeskim:mentions | umls-concept:C1335824 | lld:lifeskim |
pubmed-article:17559649 | lifeskim:mentions | umls-concept:C0086222 | lld:lifeskim |
pubmed-article:17559649 | lifeskim:mentions | umls-concept:C0205396 | lld:lifeskim |
pubmed-article:17559649 | lifeskim:mentions | umls-concept:C0524865 | lld:lifeskim |
pubmed-article:17559649 | lifeskim:mentions | umls-concept:C0680948 | lld:lifeskim |
pubmed-article:17559649 | lifeskim:mentions | umls-concept:C1709461 | lld:lifeskim |
pubmed-article:17559649 | lifeskim:mentions | umls-concept:C1705733 | lld:lifeskim |
pubmed-article:17559649 | pubmed:issue | 6 | lld:pubmed |
pubmed-article:17559649 | pubmed:dateCreated | 2008-1-16 | lld:pubmed |
pubmed-article:17559649 | pubmed:abstractText | Cis-regulatory modules of developmental genes are targets of evolutionary changes that underlie the morphologic diversity of animals. Little is known about the 'grammar' of interactions between transcription factors and cis-regulatory modules and therefore about the molecular mechanisms that underlie changes in these modules, particularly after gene and genome duplications. We investigated the ar-C midline enhancer of sonic hedgehog (shh) orthologs and paralogs from distantly related vertebrate lineages, from fish to human, including the basal vertebrate Latimeria menadoensis. | lld:pubmed |
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