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pubmed-article:17555720pubmed:abstractTextA number of studies have provided evidence for genetic modulation of brain structure in unaffected family members (FM) of schizophrenia patients using conventional volumetric analysis. High-dimensional pattern classification methods have been reported to have the capacity to determine subtle and spatially complex structural patterns that distinguish schizophrenia patients from healthy control subjects using standard magnetic resonance imaging. This study investigates whether such endophenotypic patterns are found in FM via similar image analysis approaches.lld:pubmed
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pubmed-article:17555720pubmed:articleTitleUnaffected family members and schizophrenia patients share brain structure patterns: a high-dimensional pattern classification study.lld:pubmed
pubmed-article:17555720pubmed:affiliationSection of Biomedical Image Analysis, Department of Radiology, University of Pennsylvania, School of Medicine, Philadelphia, PA 19104, USA.lld:pubmed
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