Linked Life Data

17537538

Source:http://linkedlifedata.com/resource/pubmed/id/17537538

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pubmed-article:17537538pubmed:abstractTextWe retrospectively investigated the clinical usefulness of fluorodeoxyglucose positron emission tomography (FDG-PET) for evaluation of patients with limited-disease small-cell lung cancer (LD-SCLC) diagnosed by conventional staging procedures. Sixty-three patients received whole body FDG-PET scans after routine initial staging procedures. The findings of FDG-PET scans suggesting extensive-stage disease were confirmed by other imaging tests or by the patient's clinical course. FDG-PET scan findings indicated distant metastases in 6 of 63 patients. Metastatic disease was confirmed in five of these six patients (8%, 95% confidence interval: 3-18%). FDG-PET scan also detected regional lymph node metastases even in nine patients (14%) in whom computed tomography images had been negative, including contralateral lymph node metastasis in three patients. FDG-PET scan detected additional lesions in patients diagnosed as having LD-SCLC by conventional staging procedures. The therapeutic strategies were changed in 8% of patients based on the results of FDG-PET. FDG-PET scan is recommended as an initial staging tool for patients with this disease.lld:pubmed
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pubmed-article:17537538pubmed:dateRevised2008-2-25lld:pubmed
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pubmed-article:17537538pubmed:year2007lld:pubmed
pubmed-article:17537538pubmed:articleTitleDetection of unsuspected distant metastases and/or regional nodes by FDG-PET [corrected] scan in apparent limited-disease small-cell lung cancer.lld:pubmed
pubmed-article:17537538pubmed:affiliationDivision of Thoracic Oncology, National Cancer Center Hospital East, Kashiwanoha 6-5-1, Kashiwa, Chiba 277-8577, Japan. siniho@east.ncc.go.jplld:pubmed
pubmed-article:17537538pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:17537538pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
pubmed-article:17537538pubmed:publicationTypeEvaluation Studieslld:pubmed