| pubmed-article:17521298 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17521298 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:17521298 | lifeskim:mentions | umls-concept:C1704242 | lld:lifeskim |
| pubmed-article:17521298 | lifeskim:mentions | umls-concept:C0243192 | lld:lifeskim |
| pubmed-article:17521298 | lifeskim:mentions | umls-concept:C0005330 | lld:lifeskim |
| pubmed-article:17521298 | lifeskim:mentions | umls-concept:C0232539 | lld:lifeskim |
| pubmed-article:17521298 | lifeskim:mentions | umls-concept:C0524828 | lld:lifeskim |
| pubmed-article:17521298 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:17521298 | lifeskim:mentions | umls-concept:C1418776 | lld:lifeskim |
| pubmed-article:17521298 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:17521298 | pubmed:dateCreated | 2007-5-24 | lld:pubmed |
| pubmed-article:17521298 | pubmed:abstractText | The effect of peroxisome proliferator-activated receptor-alpha (PPAR-alpha) on gastric secretion and gastric cytoprotection was evaluated using five different models of gastric ulcers: acetic acid-induced chronic gastric ulcers, pylorus ligation, ethanol-induced, indomethacin-induced and ischemia-reperfusion-induced gastric ulcers. Bezafibrate, a PPAR-alpha agonist was administered at two different doses of 10 and 100 mg/kg body weight intraperitoneanally. Both doses of bezafibrate showed significant antiulcer effect in ethanol-induced, indomethacin-induced and pylorus ligation-induced gastric ulcers. Bezafibrate increased healing of ulcer in acetic acid-induced chronic gastric ulcer model. Both doses were also effective in preventing gastric lesions induced by ischemia-reperfusion. It was concluded that PPAR-alpha activation increases healing of gastric ulcers and also prevents development of gastric ulcers in rats. | lld:pubmed |
| pubmed-article:17521298 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17521298 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17521298 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:17521298 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17521298 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17521298 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17521298 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17521298 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17521298 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17521298 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17521298 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:17521298 | pubmed:issn | 0767-3981 | lld:pubmed |
| pubmed-article:17521298 | pubmed:author | pubmed-author:AsadMohammedM | lld:pubmed |
| pubmed-article:17521298 | pubmed:author | pubmed-author:PathakRahulR | lld:pubmed |
| pubmed-article:17521298 | pubmed:author | pubmed-author:Hrishikeshava... | lld:pubmed |
| pubmed-article:17521298 | pubmed:author | pubmed-author:PrasadSatyaS | lld:pubmed |
| pubmed-article:17521298 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17521298 | pubmed:volume | 21 | lld:pubmed |
| pubmed-article:17521298 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17521298 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17521298 | pubmed:pagination | 291-6 | lld:pubmed |
| pubmed-article:17521298 | pubmed:meshHeading | pubmed-meshheading:17521298... | lld:pubmed |
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| pubmed-article:17521298 | pubmed:meshHeading | pubmed-meshheading:17521298... | lld:pubmed |
| pubmed-article:17521298 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:17521298 | pubmed:articleTitle | Effect of peroxisome proliferator-activated receptor-alpha agonist (bezafibrate) on gastric secretion and gastric cytoprotection in rats. | lld:pubmed |
| pubmed-article:17521298 | pubmed:affiliation | Department of Pharmacology, Krupanidhi College of Pharmacy, #5 Sarjapur Road, Koramangala, Bangalore 560 034, India. | lld:pubmed |
| pubmed-article:17521298 | pubmed:publicationType | Journal Article | lld:pubmed |
