| pubmed-article:17516096 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17516096 | lifeskim:mentions | umls-concept:C0304925 | lld:lifeskim |
| pubmed-article:17516096 | lifeskim:mentions | umls-concept:C0005456 | lld:lifeskim |
| pubmed-article:17516096 | lifeskim:mentions | umls-concept:C1323338 | lld:lifeskim |
| pubmed-article:17516096 | lifeskim:mentions | umls-concept:C1510827 | lld:lifeskim |
| pubmed-article:17516096 | lifeskim:mentions | umls-concept:C1177210 | lld:lifeskim |
| pubmed-article:17516096 | lifeskim:mentions | umls-concept:C1707511 | lld:lifeskim |
| pubmed-article:17516096 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:17516096 | pubmed:dateCreated | 2007-7-27 | lld:pubmed |
| pubmed-article:17516096 | pubmed:abstractText | The conditional stability constant at pH 7.4 for Cu(II) binding at the N-terminal site (NTS) of human serum albumin (HSA) was determined directly by competitive UV-vis spectroscopy titrations using nitrilotriacetic acid (NTA) as the competitor in 100 mM NaCl and 100 mM N-(2-hydroxyethyl)piperazine-N'-ethanesulfonic acid (Hepes). The log Kc (NTS) value of 12.0 +/- 0.1 was determined for HSA dissolved in 100 mM NaCl. A false log log Kc (NTS) (c) value of 11.4 +/- 0.1 was obtained in the 100 mM Hepes buffer, owing to the formation of a ternary Cu(NTA)(Hepes) complex. The impact of the picomolar affinity of HSA for Cu(II) on the availability of these ions in neurodegenerative disorders is briefly discussed. | lld:pubmed |
| pubmed-article:17516096 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17516096 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17516096 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:17516096 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17516096 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17516096 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17516096 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:17516096 | pubmed:issn | 0949-8257 | lld:pubmed |
| pubmed-article:17516096 | pubmed:author | pubmed-author:BalWojciechW | lld:pubmed |
| pubmed-article:17516096 | pubmed:author | pubmed-author:Soko?owskaMag... | lld:pubmed |
| pubmed-article:17516096 | pubmed:author | pubmed-author:RózgaMa?gorza... | lld:pubmed |
| pubmed-article:17516096 | pubmed:author | pubmed-author:ProtasAnna... | lld:pubmed |
| pubmed-article:17516096 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17516096 | pubmed:volume | 12 | lld:pubmed |
| pubmed-article:17516096 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17516096 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17516096 | pubmed:pagination | 913-8 | lld:pubmed |
| pubmed-article:17516096 | pubmed:meshHeading | pubmed-meshheading:17516096... | lld:pubmed |
| pubmed-article:17516096 | pubmed:meshHeading | pubmed-meshheading:17516096... | lld:pubmed |
| pubmed-article:17516096 | pubmed:meshHeading | pubmed-meshheading:17516096... | lld:pubmed |
| pubmed-article:17516096 | pubmed:meshHeading | pubmed-meshheading:17516096... | lld:pubmed |
| pubmed-article:17516096 | pubmed:meshHeading | pubmed-meshheading:17516096... | lld:pubmed |
| pubmed-article:17516096 | pubmed:meshHeading | pubmed-meshheading:17516096... | lld:pubmed |
| pubmed-article:17516096 | pubmed:meshHeading | pubmed-meshheading:17516096... | lld:pubmed |
| pubmed-article:17516096 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:17516096 | pubmed:articleTitle | Human serum albumin coordinates Cu(II) at its N-terminal binding site with 1 pM affinity. | lld:pubmed |
| pubmed-article:17516096 | pubmed:affiliation | Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawi?skiego 5a, 02-106 Warsaw, Poland. | lld:pubmed |
| pubmed-article:17516096 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17516096 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:17516096 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:17516096 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:17516096 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:17516096 | lld:pubmed |
