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pubmed-article:17511890pubmed:abstractTextPrevious studies suggest that human RAD9 (hRad9), encoding a DNA damage checkpoint molecule, which is frequently amplified in epithelial tumor cells of breast, lung, head and neck cancer, participates in regulation of the tumor suppressor p53-dependent transactivation of pro-survival P21WAF1. This study examined the exact mechanism of the hRad9 function, especially through the phosphorylation of the C-terminus, in the transcription regulation of P21WAF1.lld:pubmed
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pubmed-article:17511890pubmed:authorpubmed-author:NishinoHirosh...lld:pubmed
pubmed-article:17511890pubmed:authorpubmed-author:YamamotoKen-i...lld:pubmed
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pubmed-article:17511890pubmed:dateRevised2009-11-18lld:pubmed
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pubmed-article:17511890pubmed:articleTitleRad9 modulates the P21WAF1 pathway by direct association with p53.lld:pubmed
pubmed-article:17511890pubmed:affiliationDepartment of Otolaryngology-Head and Neck Surgery, Jichi Medical University School of Medicine, Tochigi, Japan. kazu-ish@jichi.ac.jp <kazu-ish@jichi.ac.jp>lld:pubmed
pubmed-article:17511890pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:17511890pubmed:publicationTypeComparative Studylld:pubmed
pubmed-article:17511890pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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