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pubmed-article:17511889pubmed:abstractTextBulimia Nervosa (BN) is believed to be caused by an interaction of genetic and environmental factors. Previous studies support the existence of a bulimia-related endophenotype as well as disturbances in serotonin (5-HT) transmission. We studied serotonin transporter (SERT) binding in BN, and to investigate the possibility of a SERT-related endophenotype for BN, did this in a sample of female twins. We hypothesized clearly reduced SERT binding in BN women as opposed to healthy women, and intermediate SERT binding in unaffected co-twins.lld:pubmed
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pubmed-article:17511889pubmed:authorpubmed-author:RissanenAilaAlld:pubmed
pubmed-article:17511889pubmed:authorpubmed-author:KaprioJaakkoJlld:pubmed
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pubmed-article:17511889pubmed:authorpubmed-author:KoskelaAnu...lld:pubmed
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pubmed-article:17511889pubmed:dateRevised2009-11-18lld:pubmed
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pubmed-article:17511889pubmed:articleTitleSerotonin transporter binding of [123I]ADAM in bulimic women, their healthy twin sisters, and healthy women: a SPET study.lld:pubmed
pubmed-article:17511889pubmed:affiliationDepartment of Clinical Physiology and Nuclear Medicine, HUSLAB/Helsinki University Central Hospital, Helsinki, Finland. anu.koskela@helsinki.filld:pubmed
pubmed-article:17511889pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:17511889pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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