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pubmed-article:17507990rdf:typepubmed:Citationlld:pubmed
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pubmed-article:17507990pubmed:issue6lld:pubmed
pubmed-article:17507990pubmed:dateCreated2007-5-17lld:pubmed
pubmed-article:17507990pubmed:abstractTextThe diagnosis of sarcomatoid mesothelioma is still a worldwide challenge and it is often difficult, both clinically and by morphological analysis, to differentiate sarcomatoid mesothelioma from synovial sarcoma, the most frequent intrathoracic sarcoma. To confirm the absence of the synovial sarcoma translocation t(X; 18) (SYT-SSX) in sarcomatoid mesothelioma, and to test its usefulness differentiating sarcomatoid mesothelioma from synovial sarcoma, 28 tumours were examined using the reverse transcriptase-polymerase chain reaction. RNA was extracted from paraffin blocks using standard methods, reverse-transcribed and PCR performed. Molecular analysis completed in two independent laboratories showed that sarcomatoid mesothelioma samples were negative for the t(X-18). This result confirms the usefulness of this analysis in differentiating sarcomatoid mesothelioma from synovial sarcoma.lld:pubmed
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pubmed-article:17507990pubmed:authorpubmed-author:CapronFrédéri...lld:pubmed
pubmed-article:17507990pubmed:authorpubmed-author:BenhattarJean...lld:pubmed
pubmed-article:17507990pubmed:authorpubmed-author:GuillouLouisLlld:pubmed
pubmed-article:17507990pubmed:authorpubmed-author:BurkeLouiseLlld:pubmed
pubmed-article:17507990pubmed:authorpubmed-author:BegueretHugue...lld:pubmed
pubmed-article:17507990pubmed:authorpubmed-author:Galateau-Sall...lld:pubmed
pubmed-article:17507990pubmed:authorpubmed-author:VignaudJean...lld:pubmed
pubmed-article:17507990pubmed:authorpubmed-author:WeinbreckNico...lld:pubmed
pubmed-article:17507990pubmed:issnTypePrintlld:pubmed
pubmed-article:17507990pubmed:volume20lld:pubmed
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pubmed-article:17507990pubmed:pagination617-21lld:pubmed
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pubmed-article:17507990pubmed:year2007lld:pubmed
pubmed-article:17507990pubmed:articleTitleSYT-SSX fusion is absent in sarcomatoid mesothelioma allowing its distinction from synovial sarcoma of the pleura.lld:pubmed
pubmed-article:17507990pubmed:affiliationDepartement de Pathologie, CHU de Nancy and EMI 014, Nancy, France.lld:pubmed
pubmed-article:17507990pubmed:publicationTypeJournal Articlelld:pubmed