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pubmed-article:17502138pubmed:abstractTextSurface-rigidified cerasomes (ceramic-coated liposomes) are neither fused nor cross-linked when bound to siRNA (short duplex RNA) but not to plasmid DNA (long duplex DNA) which induces cross-linking. Non-ceramic reference liposomes are easily fused by the siRNA. The cerasome can thus be used as a viral-size siRNA-carrier in a wide range of concentration for RNAi silencing of exogenous and endogenous genes.lld:pubmed
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pubmed-article:17502138pubmed:authorpubmed-author:MatsuiKazukiKlld:pubmed
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pubmed-article:17502138pubmed:authorpubmed-author:KomatsuTakayo...lld:pubmed
pubmed-article:17502138pubmed:authorpubmed-author:MukaiMasaruMlld:pubmed
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pubmed-article:17502138pubmed:articleTitleRNAi gene silencing using cerasome as a viral-size siRNA-carrier free from fusion and cross-linking.lld:pubmed
pubmed-article:17502138pubmed:affiliationDepartment of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Kyoto 615-8510, Japan.lld:pubmed
pubmed-article:17502138pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:17502138pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed