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pubmed-article:17456153pubmed:dateCreated2007-4-25lld:pubmed
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pubmed-article:17456153pubmed:abstractTextPooled nucleic acid amplification techniques (NAT) and donor screening for anti-hepatitis C virus (HCV) have reduced the diagnostic window period of HCV infection in the blood donor population from about 12 to 1 or 2 weeks. During that time, HCV RNA is hardly detectable by pooled or individual donation NAT. Here we describe a case of transfusion-acquired HCV infection from an extremely low-titre donation. After a repeat donor tested positive for HCV, a look-back procedure was initiated. A recipient of a red cell concentrate from the previous donation was identified and found to be infected with HCV as well. We compared several commercial NAT systems for their ability to detect the viraemic plasma.lld:pubmed
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pubmed-article:17456153pubmed:statusMEDLINElld:pubmed
pubmed-article:17456153pubmed:monthMaylld:pubmed
pubmed-article:17456153pubmed:issn0042-9007lld:pubmed
pubmed-article:17456153pubmed:authorpubmed-author:TrobischHHlld:pubmed
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pubmed-article:17456153pubmed:volume92lld:pubmed
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pubmed-article:17456153pubmed:pagination297-301lld:pubmed
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pubmed-article:17456153pubmed:year2007lld:pubmed
pubmed-article:17456153pubmed:articleTitleFirst case of hepatitis C virus transmission by a red blood cell concentrate after introduction of nucleic acid amplification technique screening in Germany: a comparative study with various assays.lld:pubmed
pubmed-article:17456153pubmed:affiliationInstitute for Clinical Haemostaseology, Duisburg, Germany. ek@trobisch.delld:pubmed
pubmed-article:17456153pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:17456153pubmed:publicationTypeComparative Studylld:pubmed
pubmed-article:17456153pubmed:publicationTypeCase Reportslld:pubmed