| pubmed-article:17445305 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17445305 | lifeskim:mentions | umls-concept:C0237401 | lld:lifeskim |
| pubmed-article:17445305 | lifeskim:mentions | umls-concept:C0439849 | lld:lifeskim |
| pubmed-article:17445305 | lifeskim:mentions | umls-concept:C0205487 | lld:lifeskim |
| pubmed-article:17445305 | lifeskim:mentions | umls-concept:C0449438 | lld:lifeskim |
| pubmed-article:17445305 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:17445305 | pubmed:dateCreated | 2007-4-20 | lld:pubmed |
| pubmed-article:17445305 | pubmed:abstractText | Human immunodeficiency virus (HIV)-infected adults frequently evidence both neurocognitive and psychiatric dysfunction. It was hypothesized that apathy and irritability, but not anxiety and depression, are related to HIV effects on frontal-subcortical systems. This hypothesis was evaluated by determining the degree to which these psychiatric features are associated with neurocognitive functioning that is dependent upon frontal-subcortical circuitry and, therefore, thought to be sensitive to the central nervous system effects of HIV. Rating scales assessing irritability, apathy, depression, and anxiety and a dual-task paradigm were administered to 189 HIV-seropositive (HIV+) and 53 HIV-seronegative participants. Deficits in dual-task performance and greater anxiety, depression, apathy, and irritability were observed in HIV+ participants. Simultaneous multivariate regression and communality analyses revealed that only apathy and irritability were associated with dual-task performance in HIV+ participants. Thus, these findings suggest that apathy and irritability, but not depression and anxiety, are likely associated with the effects of HIV on frontal-subcortical circuitry. | lld:pubmed |
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| pubmed-article:17445305 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17445305 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17445305 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:17445305 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17445305 | pubmed:month | May | lld:pubmed |
| pubmed-article:17445305 | pubmed:issn | 1355-6177 | lld:pubmed |
| pubmed-article:17445305 | pubmed:author | pubmed-author:ColeMichael... | lld:pubmed |
| pubmed-article:17445305 | pubmed:author | pubmed-author:CastellonStev... | lld:pubmed |
| pubmed-article:17445305 | pubmed:author | pubmed-author:HinkinCharles... | lld:pubmed |
| pubmed-article:17445305 | pubmed:author | pubmed-author:BarclayTerry... | lld:pubmed |
| pubmed-article:17445305 | pubmed:author | pubmed-author:ReinhardMatth... | lld:pubmed |
| pubmed-article:17445305 | pubmed:author | pubmed-author:PerkinsAdam... | lld:pubmed |
| pubmed-article:17445305 | pubmed:author | pubmed-author:UrenoOscar... | lld:pubmed |
| pubmed-article:17445305 | pubmed:author | pubmed-author:RobinetMarta... | lld:pubmed |
| pubmed-article:17445305 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17445305 | pubmed:volume | 13 | lld:pubmed |
| pubmed-article:17445305 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17445305 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17445305 | pubmed:pagination | 549-54 | lld:pubmed |
| pubmed-article:17445305 | pubmed:dateRevised | 2010-12-3 | lld:pubmed |
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| pubmed-article:17445305 | pubmed:meshHeading | pubmed-meshheading:17445305... | lld:pubmed |
| pubmed-article:17445305 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:17445305 | pubmed:articleTitle | Relationship between psychiatric status and frontal-subcortical systems in HIV-infected individuals. | lld:pubmed |
| pubmed-article:17445305 | pubmed:affiliation | Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, California 90095, USA. micole@mednet.ucla.edu | lld:pubmed |
| pubmed-article:17445305 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17445305 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
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