Butein, a tetrahydroxychalcone, inhibits nuclear factor (NF)-kappaB and NF-kappaB-regulated gene expression through direct inhibition of IkappaBalpha kinase beta on cysteine 179 residue.

Source:http://linkedlifedata.com/resource/pubmed/id/17439942

J. Biol. Chem. 2007 Jun 15 282 24 17340-50

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PMID
17439942