| pubmed-article:17420213 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17420213 | lifeskim:mentions | umls-concept:C0020792 | lld:lifeskim |
| pubmed-article:17420213 | lifeskim:mentions | umls-concept:C0003761 | lld:lifeskim |
| pubmed-article:17420213 | lifeskim:mentions | umls-concept:C0001138 | lld:lifeskim |
| pubmed-article:17420213 | lifeskim:mentions | umls-concept:C0597979 | lld:lifeskim |
| pubmed-article:17420213 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
| pubmed-article:17420213 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
| pubmed-article:17420213 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:17420213 | pubmed:dateCreated | 2007-5-22 | lld:pubmed |
| pubmed-article:17420213 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17420213 | pubmed:abstractText | By studying the beta-lactamase content of several Acinetobacter spp. isolates from Argentina, producing the expanded-spectrum beta-lactamases (ESBL) VEB-1a or PER-2, a novel Ambler class A beta-lactamase gene was identified. It encoded the narrow-spectrum beta-lactamase SCO-1, whose activity was inhibited by clavulanic acid. SCO-1 hydrolyzes penicillins at a high level and cephalosporins and carbapenems at a very low level. beta-Lactamase SCO-1 was identified from unrelated VEB-1a-positive or PER-2-positive Acinetobacter spp. isolates recovered from three hospitals. The bla(SCO-1) gene was apparently located on a plasmid of ca. 150 kb from all cases but was not associated with any ESBL-encoding gene. The G+C content of the bla(SCO) gene was 52%, a value that does not correspond to that of the A. baumannii genome (39%). beta-Lactamase SCO-1 shares 47% amino acid identity with CARB-5 and ca. 40% with the enzymes TEM, SHV, and CTX-M. A gene encoding a putative resolvase was identified downstream of the bla(SCO-1) gene, but its precise way of acquisition remains to be determined. | lld:pubmed |
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| pubmed-article:17420213 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17420213 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17420213 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:17420213 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17420213 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:17420213 | pubmed:issn | 0066-4804 | lld:pubmed |
| pubmed-article:17420213 | pubmed:author | pubmed-author:PoirelLaurent... | lld:pubmed |
| pubmed-article:17420213 | pubmed:author | pubmed-author:NordmannPatri... | lld:pubmed |
| pubmed-article:17420213 | pubmed:author | pubmed-author:PetroniAlejan... | lld:pubmed |
| pubmed-article:17420213 | pubmed:author | pubmed-author:GalasMarceloM | lld:pubmed |
| pubmed-article:17420213 | pubmed:author | pubmed-author:DrugeonHenriH | lld:pubmed |
| pubmed-article:17420213 | pubmed:author | pubmed-author:RapoportMelin... | lld:pubmed |
| pubmed-article:17420213 | pubmed:author | pubmed-author:CorvecStéphan... | lld:pubmed |
| pubmed-article:17420213 | pubmed:author | pubmed-author:FacconeDiegoD | lld:pubmed |
| pubmed-article:17420213 | pubmed:author | pubmed-author:CattoirVincen... | lld:pubmed |
| pubmed-article:17420213 | pubmed:author | pubmed-author:PasteranFerna... | lld:pubmed |
| pubmed-article:17420213 | pubmed:author | pubmed-author:MugnierPaulin... | lld:pubmed |
| pubmed-article:17420213 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17420213 | pubmed:volume | 51 | lld:pubmed |
| pubmed-article:17420213 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17420213 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17420213 | pubmed:pagination | 2179-84 | lld:pubmed |
| pubmed-article:17420213 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:17420213 | pubmed:meshHeading | pubmed-meshheading:17420213... | lld:pubmed |
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| pubmed-article:17420213 | pubmed:meshHeading | pubmed-meshheading:17420213... | lld:pubmed |
| pubmed-article:17420213 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:17420213 | pubmed:articleTitle | Identification of the novel narrow-spectrum beta-lactamase SCO-1 in Acinetobacter spp. from Argentina. | lld:pubmed |
| pubmed-article:17420213 | pubmed:affiliation | Service de Bactériologie-Virologie, Hôpital de Bicêtre, 78 rue du Général Leclerc, 94275 Le Kremlin-Bicêtre cedex, France. | lld:pubmed |
| pubmed-article:17420213 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17420213 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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