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pubmed-article:17400462pubmed:abstractTextFour compounds were isolated from Enicosanthum membranifolium. The structures of the compounds were confirmed by spectroscopic data. Their structures were determined as N-trans-feruloyltyramine, R-(-)-mellein, clerodermic acid, and salicifoline chloride as a quaternary alkaloid compound. The structures of R-(-)-mellein and salicifoline chloride were confirmed by using X-ray diffraction. Clerodermic acid was shown to induce potent apoptosis against human leukemia HL60 cells.lld:pubmed
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pubmed-article:17400462pubmed:articleTitleThe isolation of secondary metabolites and in vitro potent anti-cancer activity of clerodermic acid from Enicosanthum membranifolium.lld:pubmed
pubmed-article:17400462pubmed:affiliationDepartment of Chemistry, Faculty of Engineering, Gifu University, Gifu 501-1193, Japan.lld:pubmed
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