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pubmed-article:17371827pubmed:abstractTextThe susceptibilities of drug-resistant hepatitis B virus (HBV) mutants to lamivudine, adefovir, tenofovir, entecavir, and 2,4-diamino-6-[2-(phosphonomethoxy)ethoxy]-pyrimidine (PMEO-DAPym), a novel acyclic pyrimidine analogue, were assessed in vitro. Most drug-resistant mutants, including multidrug-resistant strains, remained sensitive to tenofovir and PMEO-DAPym. Therefore, the latter molecule deserves further evaluation for the treatment of HBV infection.lld:pubmed
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pubmed-article:17371827pubmed:articleTitleIn vitro activity of 2,4-diamino-6-[2-(phosphonomethoxy)ethoxy]-pyrimidine against multidrug-resistant hepatitis B virus mutants.lld:pubmed
pubmed-article:17371827pubmed:affiliationINSERM, U871, 151 Cours Albert Thomas, 69424 Lyon cedex 03, France.lld:pubmed
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