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pubmed-article:17344245pubmed:abstractTextSystemic lupus erythematosus (SLE) is characterised by dysregulation of autoreactive lymphocytes and antigen-presenting cells. Signalling through Toll-like receptor 9 (TLR9), a mediator of innate immune responses, has a role in activation of dendritic cells and autoreactive B cells.lld:pubmed
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pubmed-article:17344245pubmed:articleTitleGenetic variations of Toll-like receptor 9 predispose to systemic lupus erythematosus in Japanese population.lld:pubmed
pubmed-article:17344245pubmed:affiliationDepartment of Immunology and Parasitology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto, Tokushima 770-8503, Japan.lld:pubmed
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