| pubmed-article:17340018 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17340018 | lifeskim:mentions | umls-concept:C0035647 | lld:lifeskim |
| pubmed-article:17340018 | lifeskim:mentions | umls-concept:C0033860 | lld:lifeskim |
| pubmed-article:17340018 | lifeskim:mentions | umls-concept:C0002085 | lld:lifeskim |
| pubmed-article:17340018 | lifeskim:mentions | umls-concept:C1539075 | lld:lifeskim |
| pubmed-article:17340018 | lifeskim:mentions | umls-concept:C0004083 | lld:lifeskim |
| pubmed-article:17340018 | lifeskim:mentions | umls-concept:C0062857 | lld:lifeskim |
| pubmed-article:17340018 | lifeskim:mentions | umls-concept:C0205210 | lld:lifeskim |
| pubmed-article:17340018 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:17340018 | pubmed:dateCreated | 2007-3-6 | lld:pubmed |
| pubmed-article:17340018 | pubmed:abstractText | The PSORS1 locus is the consistently replicated genetic risk factor for psoriasis. Clinical associations with the main marker allele of PSORS1, HLA-Cw6, have been addressed in a number of studies, but clinical associations have not been used as a way to distinguish the effects of the neighbouring candidate genes in PSORS1. Our results show that HLA-Cw6 and CCHCR1 risk allele associations with clinical features of psoriasis are predictably highly similar in a Finnish nationwide cohort of 379 psoriasis patients. The clinical profiling of a small group of patients (n=34) who were HLA-Cw6- but CCHCR1*WWCC positive suggested that no great differences existed between them and HCR-Cw6- patients. HCR+ genotype (as well as Cw6+ genotype) correlated for the first time positively with female sex and, in contrast with previous studies, negatively with disease severity. Presence of psoriatic arthritis was more pronounced in HCR- psoriasis (as well as in Cw6- psoriasis). Clinical profiling may be a useful approach to distinguishing genetic effects of candidate genes even within a locus in sufficiently large cohorts. | lld:pubmed |
| pubmed-article:17340018 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17340018 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17340018 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:17340018 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17340018 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17340018 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17340018 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17340018 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17340018 | pubmed:issn | 0001-5555 | lld:pubmed |
| pubmed-article:17340018 | pubmed:author | pubmed-author:HolopainenPäi... | lld:pubmed |
| pubmed-article:17340018 | pubmed:author | pubmed-author:Saarialho-Ker... | lld:pubmed |
| pubmed-article:17340018 | pubmed:author | pubmed-author:KereJuhaJ | lld:pubmed |
| pubmed-article:17340018 | pubmed:author | pubmed-author:SnellmanErnaE | lld:pubmed |
| pubmed-article:17340018 | pubmed:author | pubmed-author:SuomelaSariS | lld:pubmed |
| pubmed-article:17340018 | pubmed:author | pubmed-author:ElomaaOutiO | lld:pubmed |
| pubmed-article:17340018 | pubmed:author | pubmed-author:KarvonenSeija... | lld:pubmed |
| pubmed-article:17340018 | pubmed:author | pubmed-author:ReunalaTimoT | lld:pubmed |
| pubmed-article:17340018 | pubmed:author | pubmed-author:OnkamoPäiviP | lld:pubmed |
| pubmed-article:17340018 | pubmed:author | pubmed-author:UurasmaaTutta... | lld:pubmed |
| pubmed-article:17340018 | pubmed:author | pubmed-author:KarvonenJaakk... | lld:pubmed |
| pubmed-article:17340018 | pubmed:author | pubmed-author:HimbergJohanJ | lld:pubmed |
| pubmed-article:17340018 | pubmed:author | pubmed-author:JansénChriste... | lld:pubmed |
| pubmed-article:17340018 | pubmed:author | pubmed-author:KainuKatiK | lld:pubmed |
| pubmed-article:17340018 | pubmed:author | pubmed-author:TialaInkeriI | lld:pubmed |
| pubmed-article:17340018 | pubmed:author | pubmed-author:KoskinenLotta... | lld:pubmed |
| pubmed-article:17340018 | pubmed:author | pubmed-author:KivikäsKristi... | lld:pubmed |
| pubmed-article:17340018 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17340018 | pubmed:volume | 87 | lld:pubmed |
| pubmed-article:17340018 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17340018 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17340018 | pubmed:pagination | 127-34 | lld:pubmed |
| pubmed-article:17340018 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
| pubmed-article:17340018 | pubmed:meshHeading | pubmed-meshheading:17340018... | lld:pubmed |
| pubmed-article:17340018 | pubmed:meshHeading | pubmed-meshheading:17340018... | lld:pubmed |
| pubmed-article:17340018 | pubmed:meshHeading | pubmed-meshheading:17340018... | lld:pubmed |
| pubmed-article:17340018 | pubmed:meshHeading | pubmed-meshheading:17340018... | lld:pubmed |
| pubmed-article:17340018 | pubmed:meshHeading | pubmed-meshheading:17340018... | lld:pubmed |
| pubmed-article:17340018 | pubmed:meshHeading | pubmed-meshheading:17340018... | lld:pubmed |
| pubmed-article:17340018 | pubmed:meshHeading | pubmed-meshheading:17340018... | lld:pubmed |
| pubmed-article:17340018 | pubmed:meshHeading | pubmed-meshheading:17340018... | lld:pubmed |
| pubmed-article:17340018 | pubmed:meshHeading | pubmed-meshheading:17340018... | lld:pubmed |
| pubmed-article:17340018 | pubmed:meshHeading | pubmed-meshheading:17340018... | lld:pubmed |
| pubmed-article:17340018 | pubmed:meshHeading | pubmed-meshheading:17340018... | lld:pubmed |
| pubmed-article:17340018 | pubmed:meshHeading | pubmed-meshheading:17340018... | lld:pubmed |
| pubmed-article:17340018 | pubmed:meshHeading | pubmed-meshheading:17340018... | lld:pubmed |
| pubmed-article:17340018 | pubmed:meshHeading | pubmed-meshheading:17340018... | lld:pubmed |
| pubmed-article:17340018 | pubmed:meshHeading | pubmed-meshheading:17340018... | lld:pubmed |
| pubmed-article:17340018 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:17340018 | pubmed:articleTitle | Clinical associations of the risk alleles of HLA-Cw6 and CCHCR1*WWCC in psoriasis. | lld:pubmed |
| pubmed-article:17340018 | pubmed:affiliation | Department of Dermatology, Helsinki University Central Hospital, Helshinki, Finland. | lld:pubmed |
| pubmed-article:17340018 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17340018 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:3107 | entrezgene:pubmed | pubmed-article:17340018 | lld:entrezgene |
| entrez-gene:54535 | entrezgene:pubmed | pubmed-article:17340018 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:17340018 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:17340018 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:17340018 | lld:entrezgene |
| lhgdn:association:23219 | lhgdn:found_in | pubmed-article:17340018 | lld:lhgdn |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:17340018 | lld:pubmed |
