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pubmed-article:17338534pubmed:abstractText[structure: see text]. The use of Leloir glycosyltransferases to prepare biologically relevant oligosaccharides and glycoconjugates requires access to sugar nucleoside diphosphates, which are notoriously difficult to efficiently synthesize and purify. We report a novel stereoselective route to UDP- and GDP-alpha-D-mannose as well as UDP- and GDP-beta-L-fucose via direct displacement of acylated glycosyl bromides with nucleoside 5'-diphosphates.lld:pubmed
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pubmed-article:17338534pubmed:articleTitleStereoselective chemical synthesis of sugar nucleotides via direct displacement of acylated glycosyl bromides.lld:pubmed
pubmed-article:17338534pubmed:affiliationDepartment of Chemistry, Dalhousie University, Halifax, NS, Canada.lld:pubmed
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pubmed-article:17338534pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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