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pubmed-article:17329307pubmed:abstractTextSystemic lupus erythematosus (SLE) is associated with a high prevalence of cardiovascular disease. Circulating endothelial progenitor cells (EPCs) contribute to vascular regeneration and repair, thereby protecting against atherosclerotic disease. EPCs are derived from CD34+ haematopoietic stem cells (HSCs), which have an increased propensity for apoptosis in the bone marrow of patients with SLE.lld:pubmed
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pubmed-article:17329307pubmed:articleTitleHaematopoietic and endothelial progenitor cells are deficient in quiescent systemic lupus erythematosus.lld:pubmed
pubmed-article:17329307pubmed:affiliationDepartment of Vascular Medicine, F02.126, University Medical Centre Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands.lld:pubmed
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