| pubmed-article:17314042 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17314042 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:17314042 | lifeskim:mentions | umls-concept:C0250457 | lld:lifeskim |
| pubmed-article:17314042 | lifeskim:mentions | umls-concept:C1621296 | lld:lifeskim |
| pubmed-article:17314042 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
| pubmed-article:17314042 | lifeskim:mentions | umls-concept:C1524063 | lld:lifeskim |
| pubmed-article:17314042 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
| pubmed-article:17314042 | lifeskim:mentions | umls-concept:C1958193 | lld:lifeskim |
| pubmed-article:17314042 | pubmed:issue | 9 | lld:pubmed |
| pubmed-article:17314042 | pubmed:dateCreated | 2007-4-6 | lld:pubmed |
| pubmed-article:17314042 | pubmed:abstractText | In search of new selective antagonists and/or agonists for the human melanocortin receptor subtypes hMC1R to hMC5R to elucidate the specific biological roles of each GPCR, we modified the structures of the superagonist MT-II (Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-NH(2)) and the hMC3R/hMC4R antagonist SHU9119 (Ac-Nle-c[Asp-His-D-Nal(2')-Arg-Trp-Lys]-NH(2)) by replacing the His-d-Phe and His-d-Nal(2') fragments in MT-II and SHU9119, respectively, with Aba-Xxx (4-amino-1,2,4,5-tetrahydro-2-benzazepin-3-one-Xxx) dipeptidomimetics (Xxx=D-Phe/pCl-D-Phe/D-Nal(2')). Employment of the Aba mimetic yielded novel selective high affinity hMC3R and hMC3R/hMC5R antagonists. | lld:pubmed |
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| pubmed-article:17314042 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:17314042 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:17314042 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17314042 | pubmed:month | May | lld:pubmed |
| pubmed-article:17314042 | pubmed:issn | 0960-894X | lld:pubmed |
| pubmed-article:17314042 | pubmed:author | pubmed-author:HrubyVictor... | lld:pubmed |
| pubmed-article:17314042 | pubmed:author | pubmed-author:TourwéDirkD | lld:pubmed |
| pubmed-article:17314042 | pubmed:author | pubmed-author:MisickaAleksa... | lld:pubmed |
| pubmed-article:17314042 | pubmed:author | pubmed-author:CaiMinyingM | lld:pubmed |
| pubmed-article:17314042 | pubmed:author | pubmed-author:MayorovAlexan... | lld:pubmed |
| pubmed-article:17314042 | pubmed:author | pubmed-author:ChandlerKevin... | lld:pubmed |
| pubmed-article:17314042 | pubmed:author | pubmed-author:BalletStevenS | lld:pubmed |
| pubmed-article:17314042 | pubmed:author | pubmed-author:TymeckaDagmar... | lld:pubmed |
| pubmed-article:17314042 | pubmed:author | pubmed-author:PalmerErin... | lld:pubmed |
| pubmed-article:17314042 | pubmed:author | pubmed-author:RompaeyKaroli... | lld:pubmed |
| pubmed-article:17314042 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17314042 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:17314042 | pubmed:volume | 17 | lld:pubmed |
| pubmed-article:17314042 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17314042 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17314042 | pubmed:pagination | 2492-8 | lld:pubmed |
| pubmed-article:17314042 | pubmed:dateRevised | 2011-9-26 | lld:pubmed |
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| pubmed-article:17314042 | pubmed:meshHeading | pubmed-meshheading:17314042... | lld:pubmed |
| pubmed-article:17314042 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:17314042 | pubmed:articleTitle | Novel selective human melanocortin-3 receptor ligands: use of the 4-amino-1,2,4,5-tetrahydro-2-benzazepin-3-one (Aba) scaffold. | lld:pubmed |
| pubmed-article:17314042 | pubmed:affiliation | Department of Organic Chemistry, Vrije Universiteit Brussel, B-1050 Brussels, Belgium. sballet@vub.ac.be | lld:pubmed |
| pubmed-article:17314042 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17314042 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:17314042 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
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