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pubmed-article:17310820pubmed:abstractTextLamivudine (3TC) therapy can cause the emergence of M1841/V. Previous studies suggest a higher fidelity of the mutant reverse transcriptase and lower replication capacity of the mutant virus. No data exist from clinical comparative studies evaluating the benefit of M1841/V in patients receiving combination antiretroviral therapy (cART).lld:pubmed
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pubmed-article:17310820pubmed:articleTitleA randomized trial to evaluate continuation versus discontinuation of lamivudine in individuals failing a lamivudine-containing regimen: the COLATE trial.lld:pubmed
pubmed-article:17310820pubmed:affiliationCopenhagen HIV Programme (CHIP), Hvidovre University Hospital, Copenhagen, Denmark.lld:pubmed
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pubmed-article:17310820pubmed:publicationTypeRandomized Controlled Triallld:pubmed
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