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pubmed-article:17289751pubmed:issue6lld:pubmed
pubmed-article:17289751pubmed:dateCreated2007-4-23lld:pubmed
pubmed-article:17289751pubmed:abstractTextThe evaluation of phthalocyanine labels for the surface-enhanced resonance Raman scattering (SERRS) detection of oligonucleotides is reported. Three phthalocyanine-labelled oligonucleotides were assessed, each containing a different metal centre. Detection limits for each labelled oligonucleotide were determined using two excitation frequencies where possible. Limits of detection as low as 2.8 x 10(-11) mol. dm(-3) were obtained which are comparable to standard fluorescently labelled probes used in previous SERRS studies. The identification of two phthalocyanine-labelled oligonucleotides without separation was also demonstrated indicating their suitability for multiplexing. This study extends the range of labels suitable for quantitative surface-enhanced resonance Raman scattering with silver nanoparticles and offers more flexibility and choice when considering SERRS for quantitative DNA detection.lld:pubmed
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pubmed-article:17289751pubmed:authorpubmed-author:SmithW EWElld:pubmed
pubmed-article:17289751pubmed:authorpubmed-author:GrahamDDlld:pubmed
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pubmed-article:17289751pubmed:authorpubmed-author:KovalV VVVlld:pubmed
pubmed-article:17289751pubmed:authorpubmed-author:ChernonosovA...lld:pubmed
pubmed-article:17289751pubmed:authorpubmed-author:FauldsKKlld:pubmed
pubmed-article:17289751pubmed:issnTypeElectroniclld:pubmed
pubmed-article:17289751pubmed:volume35lld:pubmed
pubmed-article:17289751pubmed:ownerNLMlld:pubmed
pubmed-article:17289751pubmed:authorsCompleteYlld:pubmed
pubmed-article:17289751pubmed:paginatione42lld:pubmed
pubmed-article:17289751pubmed:dateRevised2010-9-15lld:pubmed
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pubmed-article:17289751pubmed:year2007lld:pubmed
pubmed-article:17289751pubmed:articleTitleQuantitative surface-enhanced resonance Raman scattering of phthalocyanine-labelled oligonucleotides.lld:pubmed
pubmed-article:17289751pubmed:affiliationCentre for Molecular Nanometrology, WestCHEM, Department of Pure and Applied Chemistry, University of Strathclyde, Glasgow, UK.lld:pubmed
pubmed-article:17289751pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:17289751pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
pubmed-article:17289751pubmed:publicationTypeEvaluation Studieslld:pubmed