| pubmed-article:172183 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:172183 | lifeskim:mentions | umls-concept:C0042776 | lld:lifeskim |
| pubmed-article:172183 | lifeskim:mentions | umls-concept:C0041432 | lld:lifeskim |
| pubmed-article:172183 | lifeskim:mentions | umls-concept:C1314792 | lld:lifeskim |
| pubmed-article:172183 | lifeskim:mentions | umls-concept:C0011847 | lld:lifeskim |
| pubmed-article:172183 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
| pubmed-article:172183 | pubmed:issue | 5991 | lld:pubmed |
| pubmed-article:172183 | pubmed:dateCreated | 1976-2-9 | lld:pubmed |
| pubmed-article:172183 | pubmed:abstractText | Sera were collected from 49 pairs of identical twins, 27 of whom were discordant (only one twin affected) and 22 concordant (both diabetic) for insulin-dependent diabetes. All were tested for antibodies to mumps, cytomegalovirus, rubella, Coxsackie virus types B1-5, and Mycoplasma pneumoniae. The diabetic co-twins had no more antibodies to any of the viruses than the non-diabetic co-twins of the discordant pairs. Antibodies to Coxsackie B2, rubella virus, and M pneumoniae were found more often in the discordant than in the concordant twins. In 30 of the 71 diabetic twins symptoms began when they were aged 4-6 years or 10-15 years. More concordant than discordant twins were diagnosed during the months January to March. Hence there was no direct evidence of a virus aetiology of juvenile onset diabetes in these twins, and the difference in antibody titres between the concordant and discordant twins was in keeping with a genetic difference between them. The age and time of onset suggested that environmental factors may be important in causing diabetes in the twins. | lld:pubmed |
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| pubmed-article:172183 | pubmed:language | eng | lld:pubmed |
| pubmed-article:172183 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:172183 | pubmed:citationSubset | AIM | lld:pubmed |
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| pubmed-article:172183 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:172183 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:172183 | pubmed:issn | 0007-1447 | lld:pubmed |
| pubmed-article:172183 | pubmed:author | pubmed-author:NelsonP GPG | lld:pubmed |
| pubmed-article:172183 | pubmed:author | pubmed-author:GambleD RDR | lld:pubmed |
| pubmed-article:172183 | pubmed:author | pubmed-author:PykeD ADA | lld:pubmed |
| pubmed-article:172183 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:172183 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:172183 | pubmed:volume | 4 | lld:pubmed |
| pubmed-article:172183 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:172183 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:172183 | pubmed:pagination | 249-51 | lld:pubmed |
| pubmed-article:172183 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:172183 | pubmed:year | 1975 | lld:pubmed |
| pubmed-article:172183 | pubmed:articleTitle | Viruses and the aetiology of diabetes: a study in identical twins. | lld:pubmed |
| pubmed-article:172183 | pubmed:publicationType | Journal Article | lld:pubmed |
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