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| pubmed-article:17195849 | lifeskim:mentions | umls-concept:C0596988 | lld:lifeskim |
| pubmed-article:17195849 | lifeskim:mentions | umls-concept:C0243077 | lld:lifeskim |
| pubmed-article:17195849 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:17195849 | pubmed:dateCreated | 2007-1-19 | lld:pubmed |
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| pubmed-article:17195849 | pubmed:abstractText | Huntington disease (HD) is an inherited neurodegenerative disorder with unclear pathophysiology. We developed a high-throughput assay in a neuronal cell culture model of HD, screened 43,685 compounds and identified 29 novel selective inhibitors of cell death in mutant huntingtin-expressing cells. Four compounds were active in diverse HD models, which suggests a role for cell death in HD; these compounds are mechanistic probes and potential drug leads for HD. | lld:pubmed |
| pubmed-article:17195849 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17195849 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17195849 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:17195849 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17195849 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:17195849 | pubmed:issn | 1552-4450 | lld:pubmed |
| pubmed-article:17195849 | pubmed:author | pubmed-author:VarmaHemantH | lld:pubmed |
| pubmed-article:17195849 | pubmed:author | pubmed-author:CattaneoElena... | lld:pubmed |
| pubmed-article:17195849 | pubmed:author | pubmed-author:StockwellBren... | lld:pubmed |
| pubmed-article:17195849 | pubmed:author | pubmed-author:LoDonald CDC | lld:pubmed |
| pubmed-article:17195849 | pubmed:author | pubmed-author:VoisineCindyC | lld:pubmed |
| pubmed-article:17195849 | pubmed:author | pubmed-author:HartAnne CAC | lld:pubmed |
| pubmed-article:17195849 | pubmed:author | pubmed-author:DeMarcoC... | lld:pubmed |
| pubmed-article:17195849 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17195849 | pubmed:volume | 3 | lld:pubmed |
| pubmed-article:17195849 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17195849 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17195849 | pubmed:pagination | 99-100 | lld:pubmed |
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| pubmed-article:17195849 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:17195849 | pubmed:articleTitle | Selective inhibitors of death in mutant huntingtin cells. | lld:pubmed |
| pubmed-article:17195849 | pubmed:affiliation | Department of Biological Sciences, Columbia University, Fairchild Center, MC 2406, 1212 Amsterdam Avenue, New York, New York 10027, USA. | lld:pubmed |
| pubmed-article:17195849 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17195849 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:17195849 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
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