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pubmed-article:17181142pubmed:abstractTextThis study was aimed at evaluating, on a limited number of benzopyran compounds, whether the insertion of an electron-rich spirocyclic substituent at the C4 carbon of the benzopyran molecular nucleus may improve the cardioprotective properties against ischemia. Some of the new compounds (1b, 2b, and 4b) exhibited interesting anti-ischemic properties without affecting significantly the blood pressure parameters.lld:pubmed
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pubmed-article:17181142pubmed:articleTitleNew benzopyran-based openers of the mitochondrial ATP-sensitive potassium channel with potent anti-ischemic properties.lld:pubmed
pubmed-article:17181142pubmed:affiliationDipartimento di Scienze Farmaceutiche and Dipartimento di Psichiatria, Neurobiologia, Farmacologia e Biotecnologie, Università di Pisa, Via Bonanno 6, I-56126 Pisa, Italy.lld:pubmed
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