| pubmed-article:17153339 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17153339 | lifeskim:mentions | umls-concept:C0026391 | lld:lifeskim |
| pubmed-article:17153339 | lifeskim:mentions | umls-concept:C0679199 | lld:lifeskim |
| pubmed-article:17153339 | lifeskim:mentions | umls-concept:C1154410 | lld:lifeskim |
| pubmed-article:17153339 | pubmed:dateCreated | 2006-12-11 | lld:pubmed |
| pubmed-article:17153339 | pubmed:abstractText | Venomous marine molluscs belonging to the genus Conus (cone snails) utilize a unique neurochemical strategy to capture their prey. Their venom is composed of a complex mixture of highly modified peptides (conopeptides) that interact with a wide range of neuronal targets. In this chapter, we describe a set of modifications based upon the hydroxylation of polypeptidic chains that are defining within the neurochemical strategy used by cone snails to capture their prey. In particular, we present a differential hydroxylation strategy that affects the neuronal targeting of a new set of a-conotoxins, mini-M conotoxins, conophans, and y-hydroxyconophans. Differential hydroxylation, preferential hydroxylation and hyperhydroxylation have been observed in these conopeptide families as a means of augmenting the venom arsenal used by cone snails for neuronal targeting and prey capture. | lld:pubmed |
| pubmed-article:17153339 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17153339 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17153339 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17153339 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17153339 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:17153339 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17153339 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17153339 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17153339 | pubmed:issn | 0079-6484 | lld:pubmed |
| pubmed-article:17153339 | pubmed:author | pubmed-author:FrancoAA | lld:pubmed |
| pubmed-article:17153339 | pubmed:author | pubmed-author:MoriLL | lld:pubmed |
| pubmed-article:17153339 | pubmed:author | pubmed-author:OaksJ HJH | lld:pubmed |
| pubmed-article:17153339 | pubmed:author | pubmed-author:FieldsG BGB | lld:pubmed |
| pubmed-article:17153339 | pubmed:author | pubmed-author:MollerCC | lld:pubmed |
| pubmed-article:17153339 | pubmed:author | pubmed-author:PisarewiczKK | lld:pubmed |
| pubmed-article:17153339 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17153339 | pubmed:volume | 43 | lld:pubmed |
| pubmed-article:17153339 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17153339 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17153339 | pubmed:pagination | 83-103 | lld:pubmed |
| pubmed-article:17153339 | pubmed:dateRevised | 2007-12-3 | lld:pubmed |
| pubmed-article:17153339 | pubmed:meshHeading | pubmed-meshheading:17153339... | lld:pubmed |
| pubmed-article:17153339 | pubmed:meshHeading | pubmed-meshheading:17153339... | lld:pubmed |
| pubmed-article:17153339 | pubmed:meshHeading | pubmed-meshheading:17153339... | lld:pubmed |
| pubmed-article:17153339 | pubmed:meshHeading | pubmed-meshheading:17153339... | lld:pubmed |
| pubmed-article:17153339 | pubmed:meshHeading | pubmed-meshheading:17153339... | lld:pubmed |
| pubmed-article:17153339 | pubmed:meshHeading | pubmed-meshheading:17153339... | lld:pubmed |
| pubmed-article:17153339 | pubmed:meshHeading | pubmed-meshheading:17153339... | lld:pubmed |
| pubmed-article:17153339 | pubmed:meshHeading | pubmed-meshheading:17153339... | lld:pubmed |
| pubmed-article:17153339 | pubmed:meshHeading | pubmed-meshheading:17153339... | lld:pubmed |
| pubmed-article:17153339 | pubmed:meshHeading | pubmed-meshheading:17153339... | lld:pubmed |
| pubmed-article:17153339 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:17153339 | pubmed:articleTitle | Hyperhydroxylation: a new strategy for neuronal targeting by venomous marine molluscs. | lld:pubmed |
| pubmed-article:17153339 | pubmed:affiliation | Department of Chemistry & Biochemistry, Centre of Excellence in Biomedical and Marine Biotechnology, Florida Atlantic University, 777 Glades Rd., Boca Raton, 33431 Florida, USA. | lld:pubmed |
| pubmed-article:17153339 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17153339 | pubmed:publicationType | Review | lld:pubmed |
| pubmed-article:17153339 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:17153339 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:17153339 | lld:pubmed |
