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pubmed-article:17145048pubmed:abstractTextIn chronic heart failure (CHF) the myocardial expression of the inflammatory cytokine tumor necrosis factor alpha (TNF-alpha), which is thought to contribute to myocardial remodeling, was found to be increased. However, it is unknown whether the E3-ubiquitin ligases MAFbx and Murf-1 are involved in this remodeling process and whether their expression is regulated by TNF-alpha.lld:pubmed
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pubmed-article:17145048pubmed:affiliationUniversity Leipzig-Heart Center Leipzig, Department of Cardiology, Leipzig, Germany. adav@medizin.uni-leipzig.delld:pubmed
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