Linked Life Data

17120031

Source:http://linkedlifedata.com/resource/pubmed/id/17120031

Statements in which the resource exists.
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pubmed-article:17120031pubmed:abstractTextWe report adjunct treatment of (interferon) IFN-alpha2b (Intron-A) in a patient with complete interferon-gamma receptor R1 (IFNGR1) deficiency suffering from disseminated infection with Mycobacterium avium complex (MAC) resistant to multiple anti-mycobacterial agents. A low dose of IFN-alpha2b (3 x 10(6) units/m(2) three times weekly subcutaneously) successfully attenuated progressive hepatosplenomegaly and abdominal/retroperitoneal/pelvic lymphadenopathy, although the patient continued to be mycobacteremic. This is the first report of a complete IFNGR1 deficiency treated with adjuvant IFN-alpha2b for disseminated MAC infection.lld:pubmed
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pubmed-article:17120031pubmed:articleTitleAdjunctive treatment of disseminated Mycobacterium avium complex infection with interferon alpha-2b in a patient with complete interferon-gamma receptor R1 deficiency.lld:pubmed
pubmed-article:17120031pubmed:affiliationDivision of Pulmonology, Allergy/Immunology, and Infectious Diseases, Department of Pediatrics, New Jersey Medical School/UMDNJ, 185 South Orange Avenue, Newark, NJ 07101-1709, USA.lld:pubmed
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